2005
DOI: 10.1007/s00595-004-3051-7
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Results of Surgery for Toxic Multinodular Goiter

Abstract: TMG is characterized by a long evolution time and is most effectively treated by total thyroidectomy, which achieves complete remission from symptoms, without relapse, and is necessary if there is associated carcinoma. However, the incidence of complications may be high if this procedure is not carried out by surgeons with experience in endocrine surgery.

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Cited by 44 publications
(27 citation statements)
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“…The recurrence rate for patients with unilateral thyroidectomy has been reported to be between 1.5-34% in previous studies, although the definition of recurrence was not consistent [3,[10][11][12][13]. For example, Rios and colleagues defined recurrence as recurrent nodules on imaging, but not necessarily requiring reoperation [10].…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…The recurrence rate for patients with unilateral thyroidectomy has been reported to be between 1.5-34% in previous studies, although the definition of recurrence was not consistent [3,[10][11][12][13]. For example, Rios and colleagues defined recurrence as recurrent nodules on imaging, but not necessarily requiring reoperation [10].…”
Section: Discussionmentioning
confidence: 99%
“…Opponents of unilateral resection are concerned with the higher recurrence rates associated with this operation due to the presence of remaining thyroid tissue. Previous studies report a wide range of recurrence rates, from 1.5-34% [3,[10][11][12][13]. Given this risk, some surgeons prefer to perform a bilateral thyroidectomy in order to decrease the possibility of developing a recurrent goiter and, thus, avoid further surgical intervention.…”
Section: Introductionmentioning
confidence: 99%
“…Dobiveni rezultat temeljimo na iskustvu operatera, što navode i drugi autori. 21,[28][29][30]39,40 Koincidencija maligne bolesti žlijezde i hipertiroidizma nije rijetka. Ukupno, bez obzira na oblike bolesti, kreće se u rasponu od 2 do 15%.…”
Section: Raspravaunclassified
“…Kod nas je taj omjer išao u korist grupe s tMNS-om (10 : 5%), što još jedanput opravdava postavku o starijoj dobi kao važnom faktoru rizika od malignosti u bolesnika s hipertireozom. [39][40][41][42][43][44][45] Dobro diferencirani karcinomi štitne žlijezde kod bolesnika te dobi znatno su agresivniji i svako odgađanje njihove dijagnostike i liječenja može znatno smanjiti prognozu preživljenja. 45 Kod ukupno 11 bolesnika (8%) imali smo papilarni karcinom koji je otkriven nakon liječenja primarne bolesti te ovaj kirurški zahvat ima i važnu ulogu u ranom otkrivanju maligne bolesti štitne žlijezde.…”
Section: Raspravaunclassified
“…Currently, total thyroidectomy is regarded as the surgical procedure of choice for Graves' disease, multi-nodular toxic and non toxic nodules [70,[72][73][74]. A study by Efermidou et al reviewing 932 cases of total thyroidectomy for benign thyroid disease showed that surgery is safe and is associated with minimal morbidity.…”
Section: Surgerymentioning
confidence: 99%