Results of the seven-year prospective study of stroke patients.

Scmidt, E V; Smirnov, V E; Ryabova, V S

doi:10.1161/01.str.19.8.942

Cited by 116 publications

(88 citation statements)

References 8 publications

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“…[17][18][19] For cerebrovascular disease, previous studies also suggested that stroke recurrence, TIA, or myocardial infarction after a stroke reflects the progression of underlying vascular disease. 20,21 It is important to point out that the second TCD in the present study was performed after the onset of a recurrent event, if any. Therefore, we consider the progression of the MCA lesion to serve as a marker of the progression of the generalized atherosclerosis process.…”

Section: Discussionmentioning

confidence: 99%

Progression of Middle Cerebral Artery Occlusive Disease and Its Relationship With Further Vascular Events After Stroke

Wong

Lam

et al. 2002

Stroke

138

110

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Background-Serial changes of flow velocities of transcranial Doppler ultrasound (TCD) in symptomatic middle cerebral artery (MCA) occlusive disease may be related to the occurrence of further vascular events, but prospective data are lacking. Methods-We conducted a prospective study on patients with cerebral ischemia who were hospitalized with symptomatic MCA stenosis or occlusion. We repeated TCD examinations 6 months after the initial examinations and recorded any stroke or coronary events during this period. The changes of MCA flow velocities were categorized as normalized artery, stable artery, and progressed artery, which were determined according to the changes of MCA velocities at 6 months. Results-We studied 143 consecutive patients who had relevant MCA occlusive diseases (107 with stenosis and 36 with occlusion). At 6 months, the velocities in the MCA returned to normal in 42 patients (29%), they were stable in 80 patients (62%), and they progressed in 13 patients (9%). The number of clinical events varied significantly among the 3 groups: there were 2 patients (4.8%) with clinical events in the normal group, 11 patients (12.5%) with clinical events in the stable group, and 5 patients (38.5%) with clinical events in the progressed group (Pϭ0.004). The 18 recurrent events included 10 recurrent strokes, 5 transient ischemic attacks, and 3 acute coronary syndromes. Conclusions-Progression

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Section: Discussionmentioning

confidence: 99%

Progression of Middle Cerebral Artery Occlusive Disease and Its Relationship With Further Vascular Events After Stroke

Wong

Lam

et al. 2002

Stroke

138

110

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“…Studies of the determinants and probabilities of survival and at various times after the index stroke have included all strokes, 3 first stroke, 4 -6 or ischemic stroke, [7][8][9][10] with emphasis on stroke subtype, 11 age, 12 or place of management. 13 The absolute risk for death after a stroke is an appropriate variable in analyses of prognostic factors, but the inferences to be drawn from the absolute survival probability may be limited because most stroke patients were in their 70s or 80s.…”

mentioning

confidence: 99%

Long-Term Survival and Causes of Death After Stroke

Brønnum-Hansen

Davidsen

Thorvaldsen

2001

Stroke

394

264

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Background and Purpose-As part of the Danish contribution to the World Health Organization (WHO) MONICA (Monitoring Trends and Determinants in Cardiovascular Disease) Project, a register of patients with stroke was established in 1982. The purpose of the present study was to analyze long-term survival and causes of death after a first stroke and to compare them with those of the background population. Methods-The study population comprised all subjects aged 25 years or older who were resident in a geographically defined region in Copenhagen County. All stroke events in the study population during 1982-1991 were ascertained and validated according to standardized criteria outlined for the WHO MONICA Project. After completion of the stroke registry at the end of 1991, all patients were followed up by record linkage to official registries. Standardized mortality ratios were calculated for various causes of death and periods after the stroke. Results-The estimated cumulative risks for death at 28 days, 1 year, and 5 years after onset were 28%, 41%, and 60%, respectively. Compared with the general population, nonfatal stroke was associated with an almost 5-fold increase in risk for death between 4 weeks and 1 year after a first stroke and a 2-fold increase in the risk for death subsequent to 1 year. The excess mortality rate in stroke patients was due mainly to cardiovascular diseases but also to cancer, other diseases, accidents, and suicide. The probability for long-term survival improved significantly during the observation period for patients with ischemic or ill-defined stroke. Conclusions-Stroke is a medical emergency associated with a very high risk for death in the acute and subacute phases and with a continuous excess risk of death. Better prevention and management of strokes may improve the long-term survival rate.

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“…The risk of vascular disorders in the central nervous system is increased by 6-25% per 1 mmol / l of the increased total cholesterol, and twice in the case of diabetes [18,20]. Schmidt and co-authors have indicated that the risk of the reoccurrence of stroke within the period of 7 years after the first episode, takes place in 28% of patients, a second relapse within the same period relates to 3% of patients and the third one to 0.6% of patients [21].…”

Section: Discussionmentioning

confidence: 99%

The Influence of Age Advancement and of Comorbidities on the Functional Capacity of Patients After the Incident of Ischemic Stroke

Haor¹,

Głowacka²,

Kalinowska³

2015

PNIN

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Introduction. The occurrence of ischemic strokes, particularly with people over 65 years of age, results from the presence of comorbidities that may adversely affect both the early and late prognosis as well as functional capacities of patients. Aim. The aim of the study was to evaluate the efficiency regarding basic daily activities performed by patients after the incident of the ischemic stroke, depending on the advancement of their age and the on the presence of comorbidities. Material and Methods. The study was carried out among 65 patients hospitalised due to the ischemic stroke in the neurology ward of the Provincial Hospital in Plock. The analysis of the functional capacity of patients, with the use of the Barthel Scale Questionnaire, was performed twice: on the first day of their hospitalisation and on the day of discharge from the hospital ward. Results. The functional capacity of the patients within the period of hospitalization after the incident of ischemic stroke was improving as a result of treatment, rehabilitation and care. However, both on the day of admission to the ward, as well as at discharge, the patients aged over 65 had the lowest scores on the Barthel Scale Questionnaire. The presence of comorbidities, particularly among older respondents, contributed to the deterioration of patients' functional capacity. Conclusions. 1). Patients after the incident of ischemic stroke, despite the improvement regarding their functional capacity, require assistance in the performance of daily activities. 2). Age advancement contributes to the reduction of the functional capacity of respondents after the incident of ischemic stroke. 3). Comorbidities of the incident of ischemic stroke as well as the prior episode of stroke significantly contribute to the decrease the functional capacity of respondents. ( JNNN 2015;4(3):102-108)

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Results of the seven-year prospective study of stroke patients.

Cited by 116 publications

References 8 publications

Progression of Middle Cerebral Artery Occlusive Disease and Its Relationship With Further Vascular Events After Stroke

Progression of Middle Cerebral Artery Occlusive Disease and Its Relationship With Further Vascular Events After Stroke

Long-Term Survival and Causes of Death After Stroke

The Influence of Age Advancement and of Comorbidities on the Functional Capacity of Patients After the Incident of Ischemic Stroke

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