Results of Videocapsule Endoscopy ∊ 250 Patients With Suspected Small Bowel Pathology

Abstract

We aimed to assess technical feasibility, clinical applicability, and diagnostic yield of videocapsule endoscopy (VCE) in a large group of unselected patients. VCE was performed with the Given Imaging swallowable capsule. Findings were considered diagnostic if the observed finding could explain the symptomatology of the patient. Findings were considered suspicious if an observed finding failed to completely explain the patient's symptoms. We studied 250 patients. A definite diagnosis was made in 95 patients (38%). Suspicious findings were noted in 80 patients (32%). No diagnosis was obtained in 74 patients (30%). The yield of VCE was higher in patients with suspected Crohn's disease. Mean viewing time decreased significantly from 51 +/- 14 to 30 +/- 7 minutes after reviewing 50 procedures. VCE is an important diagnostic tool, but a definite diagnosis is established in only 38% of the patients. The highest diagnostic yield is obtained in patients with suspected Crohn's disease.

Diagnostic yield of small-bowel capsule endoscopy in patients with iron-deficiency anemia: a systematic review

“…The main characteristics of the studies eligible for review are shown in Table 1. Five studies were from the United States, 22 15,16 and the Netherlands, 19,29 and 1 study each from Australia, 34 India, 32 Israel, 13 Japan, 35 Norway, 18 Spain, 20 and the United Kingdom. 25 Seven of them were prospective 15,20,21,28,[33][34][35] and 17 were retrospective studies.…”

“…25 Seven of them were prospective 15,20,21,28,[33][34][35] and 17 were retrospective studies. [12][13][14][16][17][18][19][22][23][24][25][26][27][29][30][31][32] Only 2 were multicenter studies. 12,13 In all but 4 studies (in 3, not reported 18,23,27 and 1 study 31 with EndoCapsule [Olympus, Tokyo, Japan]), SBCE explorations were performed with capsule endoscopes from Given Imaging Ltd (Yoqneam, Israel).…”

Capsule endoscopy for small-bowel evaluation in Crohn's disease

“…Some studies have demonstrated abnormal findings in more than one third of patient examinations, with an even higher yield in patients with suspected CD. 2,3 Although the yield of CE may be high, many of the abnormalities detected are not specific for CD. Minor mucosal abnormalities can be observed in almost one fifth of asymptomatic individuals 4 and in as many as two thirds of individuals regularly using nonsteroidal anti-inflammatory drugs (NSAIDs).…”

Double-balloon enteroscopy in Crohn’s disease patients suspected of small bowel activity: findings and clinical impact

“…In the past few years several studies have shown that WCE is indeed a patient-friendly investigation and is clinically useful [16][17][18][19][20]. A disadvantage of WCE in CD patients is the risk of capsule retention, which has been reported in up to 7% of CD patients.…”