Resuscitation of the moribund asthmatic

Riding, W. D.; Ambiavagar, M.

doi:10.1136/pgmj.43.498.234

Cited by 22 publications

(4 citation statements)

References 19 publications

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“…They quote observations suggesting that sympathetic activity may be partly responsible for these changes. That the position of the heart changes considerably in bronchial asthma is well demonstrated in the chest radiographs reproduced by Riding and Ambiavagar (1967). Furthermore, an erect posture is usually assumed by patients with severe bronchospasm in whom there is much sympathetic (or sympathomimetic) activity.…”

Section: Discussionmentioning

confidence: 91%

Right heart pressures in bronchial asthma

Gunstone¹

1971

Thorax

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Section: Discussionmentioning

confidence: 91%

Right heart pressures in bronchial asthma

Gunstone¹

1971

Thorax

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“…Hospital treatment usually comprised hydrocortisone (200mg intravenously four to six hourly), nebulised salbutamol or terbutaline (5-10mg initially and as necessary thereafter), aminophylline (5 mg/kg as a slow bolus intravenous injection followed by a constant infusion of 0.5 mg/kg per hour, or the constant infusion alone in patients known to be taking a sustained release theophylline preparation), and high concentration oxygen. Inhaled f agonist 15 Inhaled steroid 9 Oral theophylline (or derivative) 3 Inhaled cromoglycate 3 Other treatments 3 Assisted ventilation in severe acute asthma The mean duration of the exacerbation of asthma before admission to hospital was 32 hours (range 30 minutes to 10 days). The mean time from admission to endotracheal intubation was 18 hours (range 0-10 days).…”

Section: Patientsmentioning

confidence: 99%

Assisted ventilation in severe acute asthma.

Higgins¹,

Greening²,

Crompton³

1986

Thorax

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“…Other studies have reported death rates from 0 to 27% in those asthmatics requiring mechanical ventilation. 3,4 Because asthma is a reversible condition, each of these deaths should be considered a preventable event.…”

Section: Treatment Of Acute Severe Asthmamentioning

confidence: 99%

Treatment of Acute, Severe Asthma

Fernandez¹,

Martin²

1987

Semin Respir Crit Care Med

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Asthma is a common respiratory disorder and, thus, a common cause for hospital admissions. It occurs in all age groups and affects both sexes, but for reasons not well understood women tend to have more severe asthma than men. The severity of asthmatic episodes ranges from mild and nearly inapparent to severe, life-threatening and occasionally fatal. In 1975 it was estimated that asthma was the cause of death in 2000 patients in the United States. 1 Scoggin and coworkers 2 reported their experience with status asthmaticus in one general hospital. Between 1967 and 1975, there were 811 adults admitted for asthma, of which 21 had episodes that were severe enough to require mechanical ventilation and eight died. Other studies have reported death rates from 0 to 27% in those asthmatics requiring mechanical ventilation. 3,4 Because asthma is a reversible condition, each of these deaths should be considered a preventable event.The basic principles of pathophysiology and pharmacology are the same for the full spectrum of asthma. When assessing and managing severe asthma, two kinds of objective evaluations are important to grade the severity of the asthmatic episode. The first is to quantify the degree of airway obstruction and its effect on gas exchange through the measurement of airflow rates, arterial blood gas tensions, and pH. The second is to determine the response of these parameters to the administration of bronchodilating agents, which provides information for subsequent management. In regard to the second objective evaluation, those patients with acute attacks of asthma who do not respond promptly to standard doses of bronchodilators (beta-adrenergic agents, intravenous aminophylline) and rehydration represent a category of patients commonly designated as "status asthmaticus." When this occurs, it is critical that other therapeutic interventions be initiated. There is no oversimplification in the statement regarding status asthmaticus, "the longer it lasts, the worse it gets, and the worse it gets, the longer it lasts."

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Resuscitation of the moribund asthmatic

Cited by 22 publications

References 19 publications

Right heart pressures in bronchial asthma

Right heart pressures in bronchial asthma

Assisted ventilation in severe acute asthma.

Treatment of Acute, Severe Asthma

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