Resuscitation with albumin using BET formula keeps at bay fluid administration in burned patients. An observational study

Expert consensus on the use of human serum albumin in critically ill patients

“…During resuscitation, base excess (120%) and the lactate clearance rate (29%) were significantly increased. It also revealed that 20% HSA can be used for fluid resuscitation and for limiting the infusion volume within 48 h of burn injury [91] . In addition, several meta-analyses and reviews have revealed that HSA can reduce the volume of fluid required in burn patients in the early period of shock [92–101] …”

“…It also revealed that 20% HSA can be used for fluid resuscitation and for limiting the infusion volume within 48 h of burn injury. [91] In addition, several meta-analyses and reviews have revealed that HSA can reduce the volume of fluid required in burn patients in the early period of shock. [92][93][94][95][96][97][98][99][100][101] Patients in another before-after study were divided into two groups.…”

Different Depths May Not Determine the Fluid Resuscitation Volume in Early-stage Management of Severe Burns: A Model-comparison Retrospective Analysis of Fluid Volume Determining Factors

“…To the best of our knowledge, the relative volume of 1.5 mL/kg/%TBSA in the TMMU formula is lower than that of most of the other formulae and that reported in research studies, [20][21][22] which may support the use of colloids, as previous studies have indicated. 3,9,23 Similarly, as in a previous study, the results of the current study indicated a higher relative volume in practice than that estimated by the TMMU formula.…”

“…17 Therefore, mortality as a single outcome at the end of resuscitation is not a suitable endpoint. In recent years, most research studies on fluid resuscitation volume or formulae have usually selected patients with prespecified criteria regarding the severity of injury but without any requirements in terms of outcome (although some research has included a goal of urine output during resuscitation), 14,22,[29][30][31] whereas the endpoint was usually studied separately in other research. 24,32 In this study, we included patients who were resuscitated successfully to eliminate the effect of resuscitation failure; however, this entailed the loss of evidence that could identify the resuscitation volume as a contributory cause of the successful outcome.…”

Die Therapie des Verbrennungsschocks – die ersten 24 h und darüber hinaus

“…Parkland-Baxter: 3,5-4 ml/ kg KG/ % VKOF bis maximal 60 % VKOF berechnet, davon die Hälfte in den ersten 8 Stunden nach Trauma, die zweite Hälfte über die folgenden 16 Stunden modifizierte Brooke-Formel: 2 ml/ kg KG/ % VKOF/ 24 h Rule of 10: 10 ml/ % VKOF/ h; zusätzlich 100 ml/h für jede 10 kg über 80 kg KG Formel in den errechneten Volumenbedarf einbezogen werden [12]. Wir betrachten hierbei Humanalbumin 20 % als Kolloid der ersten Wahl im Verbrennungsschock.…”