Resveratrol, pterostilbene, and baicalein: plant-derived anti-biofilm agents

Abstract

Microbial adhesion to surfaces and the subsequent biofilm formation may result in contamination in food industry and in healthcare-associated infections and may significantly affect postoperative care. Some plants produce substances with antioxidant and antimicrobial properties that are able to inhibit the growth of food-borne pathogens. The aim of our study was to evaluate antimicrobial and anti-biofilm effect of baicalein, resveratrol, and pterostilbene on Candida albicans, Staphylococcus epidermidis, Pseudomonas aeruginosa, and Escherichia coli. We determined the minimum inhibitory concentrations (MIC), the minimum adhesion inhibitory concentration (MAIC), and the minimum biofilm eradication concentration (MBEC) by crystal violet and XTT determination. Resveratrol and pterostilbene have been shown to inhibit the formation of biofilms as well as to disrupt preformed biofilms. Our results suggest that resveratrol and pterostilbene appear potentially very useful to control and inhibit biofilm contaminations by Candida albicans, Staphylococcus epidermidis, and Escherichia coli in the food industry.

Prevention of biofilm re‐development on Ti‐6Al‐4V alloy by cometary discharge with a metallic grid

“…Total biofilm biomass was determined using a modified method based on ref. . The biofilm cells on the Ti‐6Al‐4V chip were stained in a sampler with 1 mL of crystal violet (0.1%, Carl Roth) for 20 min statically at room temperature.…”

Effects of resveratrol on cariogenic virulence properties of Streptococcus mutans

“…It is a member of the stilbene family and a precursor of other stilbenes such as viniferins and pterostilbene (trans-3,5-dimethoxy-40-hydroxystilbene). Resveratrol is known to have numerous biological functions such as antimicrobial activity, antiviral, antioxidant, anti-inflammatory, and anticancer [15,16]. But there is little work about its anti-cariogenic properties.…”

Effects of resveratrol on cariogenic virulence properties of Streptococcus mutans

“…It is a member of the stilbene family and a precursor of other stilbenes such as viniferins and pterostilbene (trans-3,5-dimethoxy-40-hydroxystilbene). Resveratrol is known to have numerous biological functions such as antimicrobial activity, antiviral, antioxidant, antiinflammatory, and anticancer [16,17]. But there is little work about its anti-cariogenic properties.…”