Retama monosperma (L.) Boiss.: A review of its uses in traditional medicine, chemical constituents, and pharmacologic activities

Benkhouili, Fatima Zahra; Moutawalli, Amina; Benzeid, Hanane; Doukkali, Anass; Zahidi, Ahmed

doi:10.1016/j.phyplu.2022.100349

Cited by 5 publications

(3 citation statements)

References 15 publications

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“…The fatty acids present in the lipid and hexane seeds and cladodes extracts of R. monosperma were analyzed using GC/MS. The results of the analysis are presented in Table 1 , which shows the presence of oleic acid (Omega 9), linoleic acid (Omega 6), linolenic acid (Omega 3), arachidic acid, myristic acid, pentadecylic acid, palmitic acid, palmitoleic acid, margaric acid, stearic acid, behenic acid, lignoceric acid, lauric acid, tricosanoic acid, palmitoleic acid, and pentadecanoic acid [ 2 , 21 , 23 , 28 ].…”

Section: Chemical Compositionmentioning

confidence: 99%

“…), known locally in the popular Arabic name as “R’tam” [ 1 ], is a spontaneous, abundant, and annual herb that belongs to the family of Fabaceae. It is endemic to the west of the Mediterranean basin, such as the Canary Islands, Portugal, Italy, southwest Spain, Macaronesia, North Africa, and northern Egypt [ 2 ]. In Morocco, it is situated in the desert areas and across the Middle Atlas and in several Moroccan natural forests [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

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A Comprehensive Review of the Pharmacological Properties and Bioactive Components of Retama monosperma

et al. 2023

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Retama monosperma L. (Boiss.) or Genista monosperma L. (Lam.), known locally as “R’tam”, is a spontaneous and annual herb that belongs to the Fabaceae family. It is native to the Mediterranean regions, specifically in the desert areas and across the Middle Atlas in Morocco. This plant has been extensively used in folk medicine and it is rich in bioactive compounds, including polyphenols, flavonoids, and alkaloids. Current research efforts are focusing on the development of novel natural drugs as alternatives to various organic and non-organic chemical products from Retama monosperma. In addition, extract, and isolated compounds obtained from different parts of the chosen plant have been described to exhibit multiple biological and pharmacological properties such as antioxidant, anti-aging, anti-inflammatory, antihypertensive, anti-helminthic, disinfectant, diuretic, and hypoglycemic effects. The plant-derived extract also acts as an antimicrobial agent, which is highly efficient in the treatment of bacterial, viral, and fungal infections. Its antiproliferative effects are associated with some mechanisms, such as the inhibition of cell cycle arrest and apoptosis. In light of these assessments, we critically highlight the beneficial effects of the flowers, stems, seeds extracts, and isolated compounds from R. monosperma (L.) Boiss in human health care, industrial, and other applications, as well as the possible ways to be employed as a potential natural source for future drug discovery.

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Section: Chemical Compositionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

A Comprehensive Review of the Pharmacological Properties and Bioactive Components of Retama monosperma

et al. 2023

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“…8,9 In addition, several studies reported the biological activities of R. monosperma, including antibacterial, anti-inammatory, antioxidant, anti-proliferative, antiulcer, antiviral, and hepatoprotective activities. 10,11 Moreover, the roots of R. monosperma are reported to contain natural antioxidants, including avonoids and phenolic compounds, making them promising candidates for the green synthesis of MNPs, including AgNPs. 10 Silver nanoparticles (AgNPs) are attracting attention as potential antibacterial agents due to their intriguing physicochemical features and innate ability to penetrate bacterial cell walls, altering the construction of cell membranes and even leading to cell death.…”

Section: Introductionmentioning

confidence: 99%

Retama monospermachemical profile, green synthesis of silver nanoparticles, and antimicrobial potential: a study supported by network pharmacology and molecular docking

Alyami,

Fakhry,

El Halfawy

et al. 2023

RSC Adv.

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Nano-phytosome loaded Retama raetam extract/colistin: antibacterial, antioxidant activities and in vivo lipopolysaccharide-induced-neurotoxicity inhibition

Elsabrouty,

Elwakil,

Salam

et al. 2024

Braz J Microbiol

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Retama monosperma (L.) Boiss.: A review of its uses in traditional medicine, chemical constituents, and pharmacologic activities

Cited by 5 publications

References 15 publications

A Comprehensive Review of the Pharmacological Properties and Bioactive Components of Retama monosperma

A Comprehensive Review of the Pharmacological Properties and Bioactive Components of Retama monosperma

Retama monospermachemical profile, green synthesis of silver nanoparticles, and antimicrobial potential: a study supported by network pharmacology and molecular docking

Nano-phytosome loaded Retama raetam extract/colistin: antibacterial, antioxidant activities and in vivo lipopolysaccharide-induced-neurotoxicity inhibition

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