2012
DOI: 10.1097/mco.0b013e32834d2259
|View full text |Cite
|
Sign up to set email alerts
|

Rethinking dietary cholesterol

Abstract: The lines of evidence coming from current epidemiological studies and from clinical interventions utilizing different types of cholesterol challenges support the notion that the recommendations limiting dietary cholesterol should be reconsidered.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1
1
1

Citation Types

0
28
1
1

Year Published

2012
2012
2020
2020

Publication Types

Select...
6
4

Relationship

0
10

Authors

Journals

citations
Cited by 46 publications
(30 citation statements)
references
References 43 publications
0
28
1
1
Order By: Relevance
“…The epidemiological literature, as well as the clinical trial evidence, does not support the idea that dietary cholesterol, and in particular egg consumption, is a risk factor for CHD or stroke in healthy adults [18], contrary to what has been observed in subjects with chronic degenerative diseases like type 2 diabetes, especially if elderly [19]. The contrasting results may be linked to the multi-factorial association between dietary cholesterol and pathogenesis of CHD, as this is influenced by genetic, lifestyle and dietary factors [20,21]. More specifically, the weak relationship of CHD and dietary cholesterol from egg consumption might be modulated by the intake of other nutrients present in eggs such as antioxidants, mainly beta-carotenoids and Vitamin E, with potential, beneficial effects of atherosclerotic plaque formation and progression [20].…”
Section: Determinants Of Global Cholesterol Concentrationscontrasting
confidence: 50%
“…The epidemiological literature, as well as the clinical trial evidence, does not support the idea that dietary cholesterol, and in particular egg consumption, is a risk factor for CHD or stroke in healthy adults [18], contrary to what has been observed in subjects with chronic degenerative diseases like type 2 diabetes, especially if elderly [19]. The contrasting results may be linked to the multi-factorial association between dietary cholesterol and pathogenesis of CHD, as this is influenced by genetic, lifestyle and dietary factors [20,21]. More specifically, the weak relationship of CHD and dietary cholesterol from egg consumption might be modulated by the intake of other nutrients present in eggs such as antioxidants, mainly beta-carotenoids and Vitamin E, with potential, beneficial effects of atherosclerotic plaque formation and progression [20].…”
Section: Determinants Of Global Cholesterol Concentrationscontrasting
confidence: 50%
“…26 Conversely large buoyant LDL may be resistant to oxidation and may even be anti -atherogenic. 27 Although the role in particle size in predicting CV events remains controversial, it may not be the total serum level of LDL that mattes as much as the relative proportion of small to large particles.…”
Section: Saturated Fat and Chd Risk Factorsmentioning
confidence: 99%
“…Additionally, meat is a source of saturated fatty acids and cholesterol [18], both of which were believed over the last few decades to increase the risk of heart disease. Although the recommendation about dietary cholesterol has become obsolete and the role of saturated fatty acids is currently being reconsidered [1921], few consumers are up to date regarding these topics.…”
Section: Introductionmentioning
confidence: 99%