“…The use of splenectomised rabbits for this purpose has been suggested by Jacobson and Williams (1945 a and bj, who found that such animals show a reticulocytosis on the fourth or fifth day after injection with potent liver extracts. These findings have received some confirmation recently from Bavin and Middleton (1946). Further experiments with splenectomised rabbits have been carried out here, and some incidental observations made on the counting of reticulocytes.…”