Retinal Artery Obstruction and Atheromas Associated With Non-Hodgkin's Large Cell Lymphoma (Reticulum Cell Sarcoma)

Gass, J. Donald M.; Trattler, Henry L.

doi:10.1001/archopht.1991.01080080094039

Cited by 66 publications

(24 citation statements)

References 15 publications

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“…The great majority of PIOL, which have an incidence of approximately 0.1% of all ocular tumours [ Clinically, PIOL can masquerade as posterior uveitis, vitritis or retinitis and represents a significant diagnostic challenge both clinically and histopathologically [6, 26, 28,31,56,60,62]. Because of its insidious onset and its ability to simulate other conditions, delays in the diagnosis of PIOL are common [11].…”

Section: Discussionmentioning

confidence: 99%

Primary intraocular lymphoma of T-cell type: report of a case and review of the literature

Coupland

Anastassiou

Bornfeld

et al. 2004

Graefe's Arch Clin Exp Ophthalmol

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A rare PIOL of T-cell type was diagnosed on the basis of vitreous aspiration and chorioretinal biopsy. In addition to conventional cytology and immunocytology, the utilisation of gene rearrangement studies on vitreous or chorioretinal biopsies increases the chances of diagnosing or excluding a PIOL of either B-cell or T-cell type. Despite its rarity, ophthalmic pathologists should always consider the diagnosis of T-PIOL when reviewing vitreous samples.

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Section: Discussionmentioning

confidence: 99%

Primary intraocular lymphoma of T-cell type: report of a case and review of the literature

Coupland

Anastassiou

Bornfeld

et al. 2004

Graefe's Arch Clin Exp Ophthalmol

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“…27,[143][144][145] It is possible that in such cases the eyes were indeed infected and the infectious process recruited various inflammatory cells, including a few B lymphocytes, into the eye. The infectious DNA might incorporate in the B lymphocytes.…”

Section: Infectious Agents May Play a Role In Piol Patho-genesis And mentioning

confidence: 99%

Molecular pathology of primary intraocular lymphoma

Chan¹

2004

American Journal of Ophthalmology

129

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“…18 All of these (except uveal melanoma) not uncommonly may have CNS involvement. Reactive lymphoid hyperplasia and spread of systemic lymphoma within the eye are the most difficult entities to distinguish from PCNSLO since they are histologically similar.…”

Section: Clinical Differential Diagnosismentioning

confidence: 99%

“…PCNSLO can cause arteriolar obstruction, resulting in retinal necrosis. 18,20 Metastatic carcinoma is the most common intraocular malignancy. Metastases typically present as yellow-white choroidal masses and frequently have mottled brown pigment in the overlying retinal pigment epithelium.…”

Section: Clinical Differential Diagnosismentioning

confidence: 99%

Intraocular Lymphoma

Bardenstein

1998

Cancer Control

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Background Primary ocular lymphoma is a distinct subtype of intraocular lymphoma. Its clinical presentation can mimic benign conditions. Diagnosis is often based on obtaining an intraocular biopsy. Optimal management is not yet realized. Methods This report combines the experience of the author with a review of the current literature pertaining to intraocular lymphoma. Results Primary ocular lymphoma, a subtype of primary central nervous system (CNS) lymphoma, has a variable clinical course and frequently mimics benign inflammatory disease. Even when suspected, diagnosis can be elusive. Chemoradiation is the most effective treatment, but significant ocular and cerebral morbidity is associated with its use. Novel treatment regimens may reduce or eliminate side effects while preserving life, vision, and CNS function. Conclusions Primary CNS lymphoma with ocular involvement should be considered in patients with refractory uveitis, yellow-white choroidal masses, and CNS lymphoma. Aggressiveness in making the diagnosis should be tempered by the potential complications of the diagnostic process and advanced by the life-threatening nature of the disease. Treatment should attempt to maximize efficacy while incorporating considerations such as extent of disease and the patient's age, health, and mental state.

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Retinal Artery Obstruction and Atheromas Associated With Non-Hodgkin's Large Cell Lymphoma (Reticulum Cell Sarcoma)

Cited by 66 publications

References 15 publications

Primary intraocular lymphoma of T-cell type: report of a case and review of the literature

Primary intraocular lymphoma of T-cell type: report of a case and review of the literature

Molecular pathology of primary intraocular lymphoma

Intraocular Lymphoma

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