Retinal complications of optic disc drusen.

Abstract

(4) elevated mounds lifting the retina and causing striae radiating from the mounds towards the macula and beyond; (5) pigmentary disturbance of the macula or a wider area of papillo-macular bundle after the resolution of acute stages which, while often clinically severe, is compatible with recovery of normal or near normal vision. It is proposed that the syndrome be designated the 'optic disc drusen retinopathy.'

Optic pit syndrome

“…When executed the results are within normal limits (Rubinstein and Ali, 1978) except for occasional electroretinograms of reduced amplitude in the presence of macular detachments (Farpour and Babel, 1968) In our cases the electroretinograms and electro-oculograms were normal due to the absence of diffuse retinal lesions. The latencies of the pattern-reversal visual evoked cortical potentials were delayed only in cases with serous detachment of the macula.…”

“…A large optic disc was found in many eyes with optic pit (Gass, 1969;Theodossiadis, 1977;Rubinstein and Ali, 1978;Apple et al, 1982). In most of our cases the anomalous optic disc showed a diameter greater than that of the contralateral eye.…”

“…In 1969 Gordon and Chatfield suggested that fluid leaking from such anomalous vessels could travel from the pit deep to the macula. However the relationship between the different fluorescein angiographic patterns of the pits and the presence or absence of macular detachment, was not emphasized in subsequent papers even though fluorescein angiographies of optic pits published in these articles seemed to demonstrate in most cases some correlation between detachment and hyperfluorescence (Gass, 1969;Theodossiadis, 1977;Rubinstein and Ali, 1978). recognized that the leakage from vessels located in the floor of the pit is generally more frequent in eyes with detachment than in eyes without detachment.…”

“…It seems better to call these discs large optic discs, rather than megalopapillas, preserving the latter term to define the anomaly exclusively characterized by a wider than normal disc surface. In addition, some of the discs with pits appear distorted and show an irregularshape (Rubinstein and Ali, 1978).…”

Echographic Diagnosis of Drusen of the Optic Nerve Head in Patients with Angioid Streaks

“…These changes have been observed in patients with PXE and in patients with no systemic disease [19,20]. A common process of abnormal mineralization might there fore be the predisposing factor both for drusen of the ONH and for angioid streaks, and might help explain why these two lesions are associated in patients with and without PXE.…”