Retinal endovascular surgery and intravitreal triamcinolone acetonide for central vein occlusion in young adults

Bynoe, Leon A.; Weiss, Jeffrey N.

doi:10.1016/s0002-9394(02)02030-5

Cited by 44 publications

(25 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In a prospective nonrandomized comparative study on 11 eyes with CRVO receiving an intravitreal injection of TA, compared with 6 eyes of a control group without intravitreal injection of TA, the gain in visual acuity was significantly (p = 0.003) higher in the study group [103]. This confirms results of other reports on the beneficial effect of intravitreal TA on macular edema and visual acuity in patients with CRVO [81,82,83,84,85,86,87,88,89,90,91,92,93,94,95,96,97,98,99]. The results additionally suggest that the increase in visual acuity after IVTA injection may not last permanently in eyes with CRVO.…”

Section: Clinical Studies: Ta As Drug Treatment For Macular Edemasupporting

confidence: 86%

“…After the first reports on the use of IVTA for the treatment of CRVO by Greenberg et al [99] and Jonas et al [104], the number of reports on the use of IVTA as therapy of CRVO have increased exponentially [93,94,95,96,97,98,99,100,101,102,103,104,105,106,107,108,109,110,111]. In a prospective nonrandomized comparative study on 11 eyes with CRVO receiving an intravitreal injection of TA, compared with 6 eyes of a control group without intravitreal injection of TA, the gain in visual acuity was significantly (p = 0.003) higher in the study group [103].…”

Section: Clinical Studies: Ta As Drug Treatment For Macular Edemamentioning

confidence: 99%

See 1 more Smart Citation

Intravitreal Triamcinolone

Tao

Jonas

2010

Ophthalmologica

View full text Add to dashboard Cite

Background: To provide an update on the intravitreal use of triamcinolone acetonide. Methods: Review of literature regarding triamcinolone-related research. Results: After the introduction of bevacizumab and ranibizumab into clinical practice, intravitreal triamcinolone has lost its leading position as the drug most often injected intravitreally. Due to its properties as a long-acting steroid, triamcinolone has still been used for various conditions such as diffuse diabetic macular edema, retinal vein occlusions, pseudophakic cystoid macular edema, chronic prephthisical ocular hypotony and uveitis, and in combination with bevacizumab or ranibizumab. The complications of intravitreal triamcinolone therapy include secondary ocular hypertension in about 40% of the eyes injected, cataract and postoperative infectious or noninfectious endophthalmitis. Conclusions: Due to its widespread biological effects as a steroid and due to a relatively large therapeutic window, intravitreal triamcinolone has remained in clinical use for a variety of intraocular disorders, and it may be a promising candidate for intravitreal medical combination therapies.

show abstract

Section: Clinical Studies: Ta As Drug Treatment For Macular Edemasupporting

confidence: 86%

Section: Clinical Studies: Ta As Drug Treatment For Macular Edemamentioning

confidence: 99%

Intravitreal Triamcinolone

Tao

Jonas

2010

Ophthalmologica

View full text Add to dashboard Cite

show abstract

“…[16][17][18][19] As macular oedema occurs with the same mechanism both in central and BRVO, we can compare our results with those in CRVO. After IVTA injection, Jonas et al 16 reported an increase in the visual acuity of a patient with cystoid macular oedema due to CRVO.…”

Section: Discussionmentioning

confidence: 70%

“…10,11 Intravitreal triamcinolone acetonide (IVTA) injection has recently been reported to be effective in macular oedema of various aetiologies. [12][13][14][15] Although there are few reports regarding the treatment of macular oedema in central retinal vein occlusion (CRVO) with IVTA injection, [16][17][18][19] there has been no previous study evaluating the efficacy of IVTA application on chronic macular oedema in BRVO that persists despite laser photocoagulation.…”

Section: Introductionmentioning

confidence: 99%

Intravitreal triamcinolone acetonide for treatment of persistent macular oedema in branch retinal vein occlusion

Özkırış

Evereklioğlu

Erkılıç

et al. 2005

Eye

View full text Add to dashboard Cite

Background To evaluate the efficacy of intravitreal triamcinolone acetonide injection on persistent macular oedema in branch retinal vein occlusion that fails to respond to previous laser photocoagulation. Material and methods A total of 19 eyes of 19 patients with persistent macular oedema due to branch retinal vein occlusion were treated with 8 mg/0.2 ml of intravitreal triamcinolone acetonide injection. The main outcome measures included best-corrected visual acuity, intraocular pressure, and macular oedema map values of Heidelberg Retinal Tomograph II (HRT II) before and after intravitreal triamcinolone injection. Results The mean follow-up time was 6.271.0 months. The mean baseline bestcorrected logarithm of minimal angle of resolution (LogMAR) value for visual acuities of the patients before intravitreal triamcinolone injection was 1.0170.16. After treatment, it was 0.5570.22 at the 1-month, 0.5670.22 at 3-month, and 0.6270.22 at the last visits and the differences were statistically significant when compared with baseline values (for each, Po0.001). The mean oedema map values on HRT II significantly decreased by 28.5% at 1-month, 23.8% at 3-month, and 23.8% at the last visit when compared with preinjection values (for each, Po0.001). Intraocular pressure elevation exceeding 21 mmHg was observed in 26.3% of eyes at 1-month, 15.7% at 3-month, and 5.2% at the last visit, but was controlled with topical antiglaucomatous medications in all eyes.

show abstract

“…[16][17][18][19] They have been applied topically as eyedrops, locally by subconjunctival, peribulbar, or by intravitreal injections, or systemically as oral medications or by intravenous or intramuscular injections. Besides their use in conditions such as proliferative diabetic retinopathy, 20 diabetic macular edema, 6 exudative AMD, 7 or central retinal vein occlusion, 21 steroids have also been applied in combination with intraocular surgery. Kö rner et al 22 reported a trend to a reduction of postoperative fibrosis after systemic cortisone therapy.…”

Section: Discussionmentioning

confidence: 99%