Retinitis Pigmentosa and Allied Disorders

Epiretinal Membrane Formation After Intravitreal Autologous Stem Cell Implantation in a Retinitis Pigmentosa Patient

“…14,15 Recent studies have questioned the potential of autologous mesenchymal stem cell transplantation for retinal degeneration. 1 More promising results have been reported with ESC transplantation. Embryonic stem cells are characterized by pluripotency.…”

“…However, there is evidence suggesting that secondary ERM is caused by retinal injury, ischemia, or inflammation. 1 Retinal pigment epithelium (RPE) and inflammatory cells could migrate and proliferate on the inner surface of the retina. The formation of ERM could be formed because of proliferation of cells.…”

“…For a long time, RP was an incurable disease and only underwent conservative treatments, including careful refraction, cataract extraction, when indicated, management of macular edema, and referral for low-vision aids. 1 Recently, new treatment approaches have been introduced for RP, including stem cell implantation therapy, 2-4 gene therapy, 5,6 and cytokine therapy. 7 Kicic et al 8 have reported that bone marrow (BM) stem cells could be differentiated into photoreceptor cells in in vivo experiments.…”

Ultra-wide field fluorescein angiography in retinitis pigmentosa with intermediate uveitis

“…CME has been reported in 11-70% of patients with RP. [ 3 ] However, reports on intermediate uveitis coexisting with RP are rare. [ 4 ] The presence of peripheral vasculitis, vascular leakage, and CME could masquerade as uveitis in RP.…”

Vascular dysfunction in retinitis pigmentosa

“…The worldwide prevalence of RP is estimated to be 1 in 5000 (Gregory‐Evans et al. ). As knowledge of the relationship between ocular haemodynamics and RP is essential in understanding the pathogenesis of the disease, a number of studies have evaluated the ocular haemodynamics and identified ocular blood flow reductions in RP.…”