Retinoblastoma metastatic to the contralateral orbit

Mohan, Kanwar; Ak, Gupta; Saini, Jagjit S.; Jalali, Subhadra; Joshi, Kusum

doi:10.1136/bjo.74.5.311

Cited by 6 publications

(4 citation statements)

References 6 publications

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“…The distant bones most commonly affected by retinoblastoma metastasis are the ribs and vertebrae, which are the most active in the haematopoietic system, especially in children [ 13 ]. Retinoblastoma metastasis to the contralateral orbit, maxilla and mandible has been reported in previous articles [ 14 , 15 ]. Metastasis to the soft tissue is very rare.…”

Section: Discussionmentioning

confidence: 98%

Metastatic retinoblastoma of the parotid and submandibular glands: a rare case report

Wang

Zhang

et al. 2017

BMC Ophthalmol

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BackgroundRetinoblastoma is the most common intraocular malignancy occurring in children. It can metastasize to the regional lymph nodes, central nervous system and distant organs usually the bones and bone marrow and very rarely to the soft tissue. Here, we report a case of unilateral retinoblastoma in a 4-year-old girl accompanied by a large metastasis of the parotid and submandibular glands that developed about 6 months previously and gradually increased in size 5 months after enucleation of the left eye.Case presentationA 4-year-old girl with a history of unilateral retinoblastoma presented with a large, painful and worsening mass (about 20 × 23 cm) of the left side of the neck. Following surgery, the orbital tumour was completely resected, and the large tumour invasion range in the left side of the neck was not resected completely. Histopathological examination revealed retinoblastoma of the orbit and the parotid and submandibular glands. After chemotherapy and additional local radiotherapy on the parotid and submandibular glands, the tumour was inactive and stable.ConclusionsDelayed detection and inappropriate management contribute to poor outcomes. Fundus examinations, education regarding the early signs of RB, and optimization of the therapeutic strategy for RB may play important roles in ocular health.

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Section: Discussionmentioning

confidence: 98%

Metastatic retinoblastoma of the parotid and submandibular glands: a rare case report

Wang

Zhang

et al. 2017

BMC Ophthalmol

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“…However, the finding of three cases of contralateral orbital recurrence in our series suggests that non-contiguous tumour spread may be an under-recognised mechanism for orbital relapse in some of these cases. Haematogenous metastasis to the ipsilateral or contralateral orbit has been reported as a mechanism for orbital recurrence, particularly to the orbital bones28 29…”

Section: Discussionmentioning

confidence: 99%

Orbital recurrence of retinoblastoma following enucleation

Kim

Kathpalia

Dunkel

et al. 2008

British Journal of Ophthalmology

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“…According to the literature, the majority of occurrences of ocular tumor spread to the contralateral eye are malignant melanoma, with infrequent reports of retinoblastoma and lymphoma ( 22 , 23 ). Bilateral primary tumors of different types are very uncommon, and our pathologic findings confirmed that both were MECs.…”

Section: Discussionmentioning

confidence: 99%

Lacrimal gland mucoepidermoid carcinoma with contralateral eye and systemic metastasis: A rare case report and review of the literature

He²

2023

Front. Oncol.

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Lacrimal gland mucoepidermoid carcinoma is very rare. It has a high risk of recurrence and metastasis, however, it rarely metastasizes to the contralateral eye in clinical practice. Here, we present a case of a 52-year-old man with lacrimal gland mucoepidermoid carcinoma who developed multiple recurrences and metastases of another eye and other sites throughout the body after receiving surgical intervention and regular radiotherapy, which will be of ophthalmic interest and unique. Clinical features, imaging findings, histopathology, treatments, and outcomes of this very rare case are provided. A literature review of previously published cases of this disease is performed, with an emphasis on the latest diagnosis and treatment. The prognosis of tumor recurrence and metastasis is poorer, surgery with a negative margin in conjunction with adjuvant therapies is crucial for preventing local recurrence and distant metastasis and enhancing the survival rate.

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Retinoblastoma metastatic to the contralateral orbit

Abstract: In a 9-month-old girl a subperiosteal metastasis of the maxillary bone developed in the contralateral orbit about one year after enucleation of a poorly differentiated retinoblastoma.

Cited by 6 publications

References 6 publications

Metastatic retinoblastoma of the parotid and submandibular glands: a rare case report

Metastatic retinoblastoma of the parotid and submandibular glands: a rare case report

Orbital recurrence of retinoblastoma following enucleation

Lacrimal gland mucoepidermoid carcinoma with contralateral eye and systemic metastasis: A rare case report and review of the literature

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