Retinopathy of Prematurity: An emerging and evolving challenge

Dogra, Mangat R; Katoch, Deeksha

doi:10.4103/ijo.ijo_783_17

Cited by 11 publications

(9 citation statements)

References 12 publications

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“…In Kenya, pre-term births are estimated at 12.3% [ 1 ]. With improved neonatal systems in developing countries, survival rates for premature infants have increased [ 2 , 3 ]. Many of these infants survive with disabilities, including visual complications.…”

Section: Introductionmentioning

confidence: 99%

Retinopathy of prematurity in Kenya: prevalence and risk factors in a hospital with advanced neonatal care

Onyango¹,

Sitati²,

Amolo³

et al. 2018

Pan Afr Med J

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IntroductionIncreased survival of preterm babies in sub-saharan Africa has held to an increasing prevalence of Retinopathy of prematurity (ROP). This study was done to determine the ROP prevalence in a hospital with advanced neonatal care in urban Kenya.MethodsA hospital-based retrospective review of the records of premature infants screened for ROP between January 2010 and December 2015. Records of all premature infants screened for ROP in the neonatal unit and outpatient eye clinic were extracted. Information on Birth weights, Gestational age, Maternal risk factors (mode of delivery, pre-eclampsia/eclampsia) and Neonatal risk factors (neonatal sepsis, days on oxygen, blood transfusion) was recorded in a questionnaire then analysed.Results103 infants were included in the study. Mean gestational age was 29.9 ± 2.2 weeks and the mean birth weight was 1280.1 ± 333.0 grams. Forty-three infants were diagnosed with ROP, a prevalence of 41.7%. Majority of these had Stage 1 or 2 ROP in Zone II, which spontaneously regressed with follow up. Nine infants were diagnosed with vision-threatening ROP (any Zone I disease or Stage 2/3 disease in Zone II with plus disease), a prevalence of 20.9%. All of these underwent laser treatment in the neonatal unit. The most significant risk factor was low gestational age. Other risk factors identified were: low birth weight and blood transfusions.ConclusionROP prevalence in sub-saharan Africa will match those in middle-income and high income countries in neonatal units with advanced care and low mortality.

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Section: Introductionmentioning

confidence: 99%

Retinopathy of prematurity in Kenya: prevalence and risk factors in a hospital with advanced neonatal care

Onyango¹,

Sitati²,

Amolo³

et al. 2018

Pan Afr Med J

View full text Add to dashboard Cite

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“…In underdeveloped and developing countries, the screening limits are higher. In highly developed countries, the gestational age limit for screening is lowered as the occurrence of ROP is limited to extremely immature babies with quality care [56][57][58][59][60][61][62][63][64][65][66] . In another weight gain based model G-ROP (Postnatal Growth and Retinopathy of Prematurity Study), GA of ≤28 weeks is an absolute inclusion criterion 26 .…”

Section: Discussionmentioning

confidence: 99%

Assessment of Neonatal Care Standard by the Predictive Model for Retinopathy of Prematurity Based on Weight Gain

Čolić

2023

ACC

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Care of extremely premature infants is in constant need for evaluation and progress. WINROP, a predictive model based on weight gain, has been developed to reduce the number of stressful examinations for retinopathy for prematurity. Validation studies of WINROP emphasize the difference of applicability in neonatal units of various practice. The aim of the study was to assess the standard of neonatal care by WINROP. Data on extremely premature infants were collected from medical records and entered in WINROP. High-and low-risk WINROP distribution and retinopathy of prematurity outcomes were analyzed. Fifty-four infants, gestational age ≤28 weeks, were included in the study after exclusion of weight related comorbidities. High risk was noted in 74% (n=40) of infants with 24% (n=13) developing retinopathy of prematurity requiring treatment. In low alarm group, there were 3 cases with severe disease. In conclusion, WINROP is not just a provider of predictive information on the severity of retinopathy of prematurity. High-risk alarm indicates the need of adjustment of nutritional strategies. Infants without pathological growth morbidities who develop severe retinopathy of prematurity in low-risk group point to other risk factors for retinopathy of prematurity to be evaluated and changed in future practice.

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“…Retinopathy of prematurity (ROP), a proliferative retinopathy among preterm/premature infants, is emerging as the leading cause of blindness in developing and middle-income countries [ 1 ]. It is becoming a major public health problem in India.…”

Section: Introductionmentioning

confidence: 99%

Challenge Accepted: Retinopathy of Prematurity (ROP) During COVID-19

Sahu¹,

Mishra²

2023

Cureus

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The World Health Organization has identified retinopathy of prematurity (ROP) as one of the emerging causes of preventable childhood blindness in developing and middle-income countries. It is becoming a major public health problem in developing countries like India and China. ROP blindness in India is increasing due to the highest number of preterm births in the world, suboptimal neonatal care, lack of awareness, screening programs and treatment not in place, and increasing numbers of neonatal intensive care units (NICUs) and special newborn care units (SNCUs) opening all over the country without appropriate ophthalmic care. On top of it, heavier and late preterm babies are developing severe ROP due to the variable quality of neonatal services and insufficient optimal eye care in the NICU and SNCU. The situation become more precarious during the coronavirus disease 2019 (COVID-19) pandemic, and it became a challenge to motivate health workers and parents to keep the screening and treatment of ROP babies in place.

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Retinopathy of Prematurity: An emerging and evolving challenge

Cited by 11 publications

References 12 publications

Retinopathy of prematurity in Kenya: prevalence and risk factors in a hospital with advanced neonatal care

Retinopathy of prematurity in Kenya: prevalence and risk factors in a hospital with advanced neonatal care

Assessment of Neonatal Care Standard by the Predictive Model for Retinopathy of Prematurity Based on Weight Gain

Challenge Accepted: Retinopathy of Prematurity (ROP) During COVID-19

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