“…30,31 All these criteria resulting from retrospective studies are defining effectiveness as a screening load associated with the number of detected advanced ROP cases and safety as the percentage of all advanced ROP cases detected by a given criterion. 10,12,[26][27][28][29][35][36][37] In this study, effectiveness is defined as the screening load associated with the number of expected missed TD-ROP cases, with the expected number of missed TD-ROP cases being an independent indicator of safety. To our knowledge, no previous studies have evaluated screening criteria based on such measures.…”