Retinopathy of prematurity — Risk factors

Gupta, Ved Prakash; Dhaliwal, Upreet; Sharma, Ram Krishan; Gupta, Piyush; Rohatgi, Jolly

doi:10.1007/bf02830827

Cited by 85 publications

(113 citation statements)

References 14 publications

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“…Similar results were shown by Agarwal et al and Gupta et.al 25,23 . In the present study, oxygen duration >10 days, C-PAP and ventilation were found to be significant risk factor on univariate analysis similar to results shown by shah et al in their study on ROP in 2005 28 .…”

Section: Resultssupporting

confidence: 89%

Incidence and Risk factors for Retinopathy of Prematurity in Neonates of weight <1.5 kg and/ or <32 weeks of Gestation in a tertiary care Hospital

2017

Int. J. Curr. Res. Med. Sci.

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Introduction: Retinopathy of prematurity affects immature retinal vasculature of premature infants. India and other developing countries are facing the third epidemic of ROP. Various risk factors for development of ROP include low gestation, low birth weight, HMD, sepsis, shock, prolonged oxygen therapy, poor nutrition and weight gain, anemia, blood transfusion, IVH. Objective: To determine incidence and risk factors of ROP in neonates of birth weight < 1500 gm and/or gestation <32 weeks. Methods: All the eligible neonates admitted in NICU at GMC, Amritsar from July 2014 to June 2015 were enrolled in this prospective observational study and all neonatal, antenatal and perinatal problems and treatments and interventions done in Neonates were recorded and screening for ROP was done by indirect opthalmoscopy at 4 weeks of postnatal age and followed up till retinal vascularization was complete. Data was analyzed statistically to find incidence and risk factors for ROP. Results: Out of 77 babies screened, 31 babies were found to have ROP of which 9 babies required treatment. The incidence of ROP in this study was 40.3% .Risk Factors for ROP found significant on univariate analysis included birth weight, CPAP , mechanical ventilation, oxygen duration more than 10 days. blood transfusion, Hyaline

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Section: Resultssupporting

confidence: 89%

Incidence and Risk factors for Retinopathy of Prematurity in Neonates of weight <1.5 kg and/ or <32 weeks of Gestation in a tertiary care Hospital

2017

Int. J. Curr. Res. Med. Sci.

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“…3 In our country, the incidence of ROP is reported to approximately range from 20 to 52% in preterm infants. [4][5][6][7][8] Changes in neonatal care have increased the survival of preterm infants and decreased the gestational age at which preterm born infants are kept 1 Department of Paediatrics, 2 Department of Ophthalmology, Dr. Sampurnanand Medical College, Jodhpur, Rajasthan, India alive, resulting in an increasing number of infants at risk for ROP. Previous studies have stated certain risk factors like prolonged oxygen therapy, anaemia needing blood transfusion, sepsis, apnoea and few others which increase the probability of developing ROP.…”

Section: Introductionmentioning

confidence: 99%

“…Previous studies have stated certain risk factors like prolonged oxygen therapy, anaemia needing blood transfusion, sepsis, apnoea and few others which increase the probability of developing ROP. [4][5][6][7][8] Visual impairment can be decreased by timely screening, thorough follow up and prompt treatment of neonates who are diagnosed with ROP and offer better overall development for the child. 9 So, a dedicated screening program is indispensable.…”

Section: Introductionmentioning

confidence: 99%

A prospective study to determine the incidence of retinopathy of prematurity at a tertiary care centre in Western Rajasthan and delineate its risk factors

Mantri¹,

Makwana²,

Goyal³

et al. 2017

Int J Contemp Pediatr

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Background: Retinopathy of Prematurity (ROP) is one of the most common causes of preventable blindness in children. Recent advances in the neonatology have increased preterm survival and so has the ROP incidence. Studies all over the world and across the country have shown a wide range for incidence of ROP and so it is difficult to gauge the exact incidence, especially in our region.Methods: This prospective observational study was conducted in neonatal units of the Department of Paediatrics, Dr. S. N. Medical College, Jodhpur for a duration of six months. All newborns delivered in hospitals associated with Dr S. N. Medical College with gestation age at birth <34weeks and 34-36weeks associated with risk factors subjected to ROP screening by indirect ophthalmoscope by a trained ophthalmologist. Neonates with congenital cataract, hazy cornea, abnormal anterior chamber and those who expired or lost to follow up before sufficient examination could be done were excluded.Results: Out of 250 newborns screened, 34 (13.6%) were found positive for ROP and out of these 34, 18 (52.94%) had stage I, 11 (32.35%) had stage II, 5 (14.7%) had stage III and none for stage IV and V. Prolonged oxygen therapy, low birth weight, apnoea and sepsis were found to be significant risk factor (p<0.05) with the relative risk of 12.49, 3.71, 3.03 and 1.91 respectively.Conclusions: ROP is a preventable cause of blindness in children. Thus, its screening is indispensable and it has to be intensified in presence of risk factors such as prolonged oxygen therapy, low birth weight, apnoea and sepsis.

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“…A study conducted at University Medical College, GTB Hospital, Delhi by Gupta et al 6 revealed Septicemia exchange transfusion, Hyaline membrane disease and Apnea as significant risk factor for ROP.…”

Section: Discussionmentioning

confidence: 99%

Incidence and Risk Factors Contributing to Rop: Study From Neonatal Care Unitsouth India

Mani¹,

Jeganathan²

2016

jemds

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The study was conducted to identify the incidence of retinopathy of prematurity among the preterm neonates treated at neonatal unit and to evaluate the associated risk factors for ROP. DESIGNProspective observational study. SETTINGNeonatal Intensive Care Unit (NICU) of Department of Paediatrics at Chengalpattu Medical College. During the study period, 159 babies were treated at the NICU and 111 babies were discharged from the unit. Among those babies who were discharged, 14 neonates were lost for followup for ROP screening. This lost to followup was 12.6% of the study population. In this study 97 infants were screened, out of which 18 infants had ROP. The rate of ROP is 18.6% in our institution and 2 out of 18 babies had threshold ROP (11.1%), who were treated with Laser therapy. KEYWORDSROP, Preterm, South India. HOW TO CITE THIS ARTICLE:

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Retinopathy of prematurity — Risk factors

Abstract: Indirect ophthalmoscopy should be performed at 4 weeks of post natal age in all preterm babies with birth weight < or = 1500 gm, and intensified in the presence of risk factors like oxygen administration, apnoea and septicemia.

Cited by 85 publications

References 14 publications

Incidence and Risk factors for Retinopathy of Prematurity in Neonates of weight <1.5 kg and/ or <32 weeks of Gestation in a tertiary care Hospital

Incidence and Risk factors for Retinopathy of Prematurity in Neonates of weight <1.5 kg and/ or <32 weeks of Gestation in a tertiary care Hospital

A prospective study to determine the incidence of retinopathy of prematurity at a tertiary care centre in Western Rajasthan and delineate its risk factors

Incidence and Risk Factors Contributing to Rop: Study From Neonatal Care Unitsouth India

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