Retinopatia Hipertensiva Em Cães E Gatos

Queiroz, Layla Lívia; Ariza, Paula; Lima, Aline Maria Meiguins de; Fíoravantí, Maria Clorínda Soares

doi:10.18677/enciclopedia_biosfera_2015_221

Cited by 2 publications

(2 citation statements)

References 16 publications

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“…The etiology of CKD has a multifactorial occurrence and it is often not possible to identify it, although acquired, congenital and familial etiologies are cited, in the same way as the etiology, CKD has different sites of origin (Table 1). CKD still has different morphophysiological segments to be compromised, in addition, it has an insidious evolution and often, when diagnosed, presents itself in a very advanced stage of renal and systemic involvement (Jericó et al, 2015;Oliveira et al, 2020;Queiroz et al, 2015).…”

Section: Etiologymentioning

confidence: 99%

Immune disorders in dogs with chronic kidney disease: Review

Sousa¹,

Souza²,

Vaz³

et al. 2022

Pubvet

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The aim of this literature review was to identify the stages of chronic kidney disease in dogs that have greater immune dysfunction and which cellular components of the innate and humoral immune system are most affected by the retention of uremic toxins. Chronic kidney disease is characterized by being a serious and irreversible disease, but common in the practice of medical clinic for dogs and cats and usually affects those of advanced age. The consequences of chronic kidney disease can expand to other systems as the disease progresses; systemic arterial hypertension, hypertensive retinopathies and secondary renal hyperparathyroidism are examples of extra-renal impairment caused by chronic kidney disease. The Interest Renal Society (IRIS), established degrees of progression of renal impairment according to serum concentrations of symmetrical creatinine and dimethylarginine, biomarkers of kidney injury, which allows aid in diagnosis, classification of the degree of nephrological and systemic impairment and treatment affected patient. Studies in human patients demonstrate that, in the terminal stages of kidney disease, there is an impairment of the immune function of these patients, which contributes to the increase in the rate of deaths related to secondary infections, cancers caused by viruses and low responsiveness to vaccines. In Veterinary Medicine, despite the scarcity of research on immunosuppression in dogs with chronic kidney disease, some have observed, in vitro and in vivo environments, dysfunction in the innate and humoral immune system of dogs with advanced chronic kidney disease, due to the proinflammatory environment resulting from the retention of uremic toxins that had their clearance affected by impaired kidney excretory function. Stage III of chronic kidney disease in dogs requires greater care, not only to prevent the disease from progressing to stage IV, but also to prevent immune disorders that may result in death. The adoption of intervention criteria and measures aimed at preventing and / or minimizing these immunological disorders depends on the expansion of research on this topic to establish better clinical management for dogs with nephrological disorder.

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Section: Etiologymentioning

confidence: 99%

Immune disorders in dogs with chronic kidney disease: Review

Sousa¹,

Souza²,

Vaz³

et al. 2022

Pubvet

View full text Add to dashboard Cite

show abstract

“…Existem associações do ômega 3 a outras substâncias como a vitamina E, selenito de sódio, gluconato de cobre, gluconato de zinco, sulfato de condroitina e glucosamina (componentes do medicamento Gerioox ® ), sendo sua eficácia descrita como excelente terapia adjuvante com efeitos renoprotetores (Veado et al, 2013). Estes componentes auxiliam reduzindo danos causados pelos radicais livres em casos de estresse oxidativo, aumentando a longevidade e melhorando a qualidade das células glomerulares (Queiroz & PUBVET v.14, n.2, a518, p.1-6, Fev., 2020 Fioravanti, 2014). Somados, todos esses benefícios representam um importante adjuvante no tratamento conservador de cães (Veado et al, 2013).…”

Section: Introductionunclassified

Gerioox® supplementation: Use in patients with serum creatinine above 1.5 mg/dl

Antunes¹,

Carvalho²,

Mencalha³

et al. 2020

Pubvet

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Drugs containing Omega 3, alone or associated with other components, such as vitamin E and selenium, have been used as great allies in treatment and preservation of renal functionality. The objective of this study was to report the effects of supplementation with Gerioox® in dogs that presented serum concentrations of creatinine above 1.5 mg/dl, regardless of the etiology presented, attended in the city of Rio de Janeiro, during the years 2018 and 2019. The 22 cases of dogs were reported, 13 males and 9 females, azotemic, divided into four groups according to the etiologies were reported: (1) hemoparasitosis, (2) Chronic kidney disease, (3) senility, (4) Other diseases (under antibiotic and anti-inflammatory treatment). After treatment of the underlying causes and after 30 days of supplementation with Gerioox®, the animals were reevaluated for serum concentrations of urea and creatinine. It was observed that 82% of the supplemented dogs presented satisfactory results. Only animals from Group 4 and two dogs from Group 2 did not obtain satisfactory results after supplementation. In addition to the improvement in the glomerular filtration rate (GFR), a recovery was observed in erythropoiesis, with 55% of the dogs presenting improvement in the hematocrit results. It was concluded that the multivitamin Gerioox® contributes to the recovery of the azotemias in supplemented animals in the 30-day treatment period.

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Retinopatia Hipertensiva Em Cães E Gatos

Cited by 2 publications

References 16 publications

Immune disorders in dogs with chronic kidney disease: Review

Immune disorders in dogs with chronic kidney disease: Review

Gerioox® supplementation: Use in patients with serum creatinine above 1.5 mg/dl

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