RETRACTED: Adherence to Cardiac Medications in Patients With Atrial Fibrillation: A Pilot Study

Pacleb, Adrienne; Lowres, Nicole; Randall, Sue; Neubeck, Lis; Gallagher, Robyn

doi:10.1016/j.hlc.2019.11.012

Cited by 5 publications

(4 citation statements)

References 34 publications

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“…Medication adherence was self-reported and relied on patients' responses to the question regarding whether they took the prescribed medication (yes/no), instead of asking patients to self-rate medication adherence (1%–100%) as per the previous study 41 . The examiner then scored the response as either 0 (no) or 1 (yes).…”

Section: Methodsmentioning

confidence: 99%

“…Cardiovascular medication knowledge and adherence were assessed using an adaptation of a previous instrument, including questionnaires and self-rating adherence 41 . The adapted instrument was pilot tested, and minor adjustments were made for the sequence of questions.…”

Section: Methodsmentioning

confidence: 99%

“…Medication knowledge was assessed by asking openended questions about medication names, timing, and dosage instead of asking yes/no questions about dosages, timing, delaying, omitting, and forgetting as per the previous instrument. 41 Patients were asked to (1) recall the names of their prescribed medications, (2) describe the timing for each medication, and (3) describe the medication dosage. The responses were cross-checked for accuracy against the list of cardiac medications prescribed on the medical record.…”

Section: Medication Knowledge and Adherencementioning

confidence: 99%

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Cognitive Function and the Relationship With Health Literacy and Secondary Prevention in Patients With Acute Coronary Syndrome at Early Discharge

et al. 2021

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Background: Cognitive impairment (CI) may contribute to difficulties in understanding and implementing secondary prevention behavior change after acute coronary syndrome (ACS), but the association is poorly understood. Objectives: The aim of this study was to explore the prevalence of CI in patients 4 weeks post ACS and the association with health literacy and secondary prevention. Methods: Patients with ACS who were free from visual deficits, auditory impairment, and dementia diagnoses were recruited and assessed 4 weeks post discharge for cognitive function (Montreal Cognitive Assessment and Hopkins Verbal Learning Test), health literacy (Newest Vital Sign), depression (Patient Health Questionnaire), physical activity (Fitbit Activity Tracker and Physical Activity Scale for the Elderly), and medication knowledge and adherence. Results: Participants (n = 45) had an average age of 65 ± 11 years, 82% were male, 64% were married/partnered, and 82% had high school education or higher. Overall CI was identified in 28.9% (n = 13/45) of the patients 4 weeks after discharge, which was composed of patients detected on both the Montreal Cognitive Assessment and Hopkins Verbal Learning Test (n = 3), patients detected on Montreal Cognitive Assessment alone (n = 6), and patients detected on Hopkins Verbal Learning Test alone (n = 4). Fewer patients with CI had adequate health literacy (61.4%) than patients with normal cognition (90.3%, P = .024). Significant correlations were found between Hopkins Verbal Learning Test scores and medication knowledge (0.4, P = .008) and adherence (0.33, P = .029). Conclusions: In this exploratory study, 30% of patients with ACS demonstrated CI at 4 weeks post discharge. Two screening instruments were required to identify all cases. Cognitive impairment was significantly associated with health literacy and worth further investigation.

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Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Medication Knowledge and Adherencementioning

confidence: 99%

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Cognitive Function and the Relationship With Health Literacy and Secondary Prevention in Patients With Acute Coronary Syndrome at Early Discharge

et al. 2021

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“…Kronish et al reported results in a low-income, minority population in New York, where medication adherence was poor in 40% of cases with more common concerns about their medication, suspicion of their treating physicians, or limited communication with healthcare providers due to language barriers [ 25 ]. Comparable studies found non-adherence rates between 38% and 41% for cardiac medication in patients with known AF [ 26 , 28 ]. A more sufficient adherence rate was reported in up to 85.2% of patients when they were involved in an improved outpatient healthcare delivery system, such as Kaiser Permanente Southern California (KPSC) [ 27 ].…”

Section: Discussionmentioning

confidence: 99%

Large-vessel-occlusion in patients with previous ischemic stroke: an analysis of adherence to secondary preventive medication for different etiologies

Kohlhase

Schäfer

Tako

et al. 2023

Neurol. Res. Pract.

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Background Large vessel occlusion (LVO) is a severe condition that carries a high risk of morbidity and mortality, underscoring the importance of effective prevention strategies. This retrospective study aimed to analyze the intake of preventive medication at the time of hospitalization in a cohort of recurrent stroke patients presenting with acute LVO. Methods The study assessed the intake of either platelet aggregation inhibitors (PAI), oral anticoagulants (OAC) or statins at admission in patients with recurrent stroke and correlated it with the final classification of LVO. The frequency of those secondary preventive medication in recurrent stroke patients was defined as primary endpoint. The Modified Rankin Scale (mRS) at discharge was used as a functional outcome and defined as a secondary outcome measure. Results This study included 866 patients who were treated for LVO between 2016 and 2020, of whom 160 (18.5%) had a recurrent ischemic stroke. OAC (25.6% vs. 14.1%, p < 0.01), PAI (50.0% vs. 26.0%, p < 0.01), or statin therapy (50.6% vs. 20.8%, p < 0.01) at admission were significantly more frequent in recurrent stroke patients compared to patients with a first-time stroke. Concerning LVO etiology in recurrent stroke patients, OAC at admission was taken in 46.8% of cardioembolic LVO, whereas PAI and statin at admission in macroangiopathic LVO were administered to 40.0%; neither PAI nor OAC was taken in 26.0%, 28.3%, and 31.6% of cardioembolic, macroangiopathic, or cryptogenic strokes, respectively. Regardless of stroke recurrence or etiology, there was an increase in mRS at discharge. Conclusions Despite high-quality healthcare, this study suggested a significant proportion of patients with recurrent stroke who were either non-adherent or insufficiently adherent to secondary preventive medication. Given the disability associated with LVO, improving patients’ medication adherence and identifying unknown stroke causes are crucial for effective prevention strategies.

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Predictors of anticoagulation adherence in patients with acute pulmonary embolism

et al. 2022

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RETRACTED: Adherence to Cardiac Medications in Patients With Atrial Fibrillation: A Pilot Study

Cited by 5 publications

References 34 publications

Cognitive Function and the Relationship With Health Literacy and Secondary Prevention in Patients With Acute Coronary Syndrome at Early Discharge

Cognitive Function and the Relationship With Health Literacy and Secondary Prevention in Patients With Acute Coronary Syndrome at Early Discharge

Large-vessel-occlusion in patients with previous ischemic stroke: an analysis of adherence to secondary preventive medication for different etiologies

Predictors of anticoagulation adherence in patients with acute pulmonary embolism

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