[Retracted] Adverse Pregnancy Outcomes Associated with Endometriosis and Its Influencing Factors

Abstract

Aim. To investigate the adverse pregnancy outcomes associated with endometriosis and its influencing factors. Methods. A total of 188 endometriosis patients who gave birth at our hospital between June 2018 and January 2021 were screened for eligibility and included in the research group, while a control group of 188 nonendometriosis women who delivered at our hospital during the same period were also included as healthy controls. Pregnancy outcomes were the key outcome measure, and the relationship between endometriosis and unfavorable pregnancy outcomes, as well as the influencing factors, were explored. Results. There was no significant difference in the risk of adverse pregnancy events such as miscarriage, ectopic pregnancy, termination of pregnancy, and fetal death between the two groups ( P > 0.05 ). The differences in hypertensive disorder in pregnancy, gestational diabetes, placental abruption, fetal growth restriction, and luteal support between the two groups also failed to reach the statistical standard ( P > 0.05 ). The two groups significantly differed in terms of cesarean delivery, preterm delivery, and placenta previa (1.92 (95% CI 1.33–2.85), 2.43 (95% CI 1.05–5.58), and 4.51 (95% CI 1.23–16.50)) ( P < 0.05 ). Conclusion. Endometriosis is an influential factor in adverse pregnancy outcomes and results in a high risk of preterm delivery, placenta previa, and cesarean delivery in patients. Mutual interactions exist among adverse pregnancy outcomes and thus require appropriate management.

The relationship between hypertensive disorders in pregnancy and endometriosis: a systematic review and meta-analysis

“…The reviewed observational studies included cohort studies (13 papers), case–control studies (7 papers), and longitudinal design (3 papers). As far as the country of origin of the studies was concerned, four were performed in Italy [ 26 – 29 ], three in Japan [ 30 – 32 ], three in China [ 6 , 33 , 34 ], three in Australia [ 18 , 35 , 36 ], two in the UK [ 17 , 37 ], two in Denmark [ 38 , 39 ], two in the USA [ 40 , 41 ], one in France [ 42 ], one in Taiwan [ 10 ], one in Sweden [ 16 ], and one in Canada [ 43 ]. The number of participants in the studies varied from 40 to 1,429,585.…”

“…Eight papers [ 10 , 29 , 32 , 34 , 37 , 40 , 41 , 43 ] assessed the overall occurrence of hypertensive disorders (combined gestational hypertension-preeclampsia) in women affected with endometriosis. The meta-analysis showed a statistically significant relationship between hypertensive disorders and endometriosis with high heterogeneity (OR = 1.17, 95% CI: 1.12, 1.22; I 2 = 93%, P < 0.00001; N = 8) (Fig.…”

Retracted: Adverse Pregnancy Outcomes Associated with Endometriosis and Its Influencing Factors

“…This article has been retracted by Hindawi, as publisher, following an investigation undertaken by the publisher [ 1 ]. This investigation has uncovered evidence of systematic manipulation of the publication and peer-review process.…”