RETRACTED ARTICLE: Forensic characterization of 15 autosomal STRs in four populations from Xinjiang, China, and genetic relationships with neighboring populations

Zhan, Xiaoni; Adnan, Atif; Yu-zhang, Zhou; Khan, Amjad; Kasim, Kadirya; McNevin, Dennis

doi:10.1038/s41598-018-22975-6

Cited by 27 publications

(17 citation statements)

References 46 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Because the autosomal STRs have been proven to be an informative marker applicable to both forensic and population genetics studies, due to their high level of variability (Rosenberg et al., 2002), we employed this set of makers to investigate the genetic structure and relationship of the ethnic Lao populations of Thailand and Laos. In this study, the forensic parameters for some populations were rather smaller than the other Asian populations (Eaaswarkhanth et al., 2009; Zhan et al., 2018). This might be because of a smaller sample size per population and the method used during sample recruitment, which used subjects from small villages.…”

Section: Discussionmentioning

confidence: 55%

Genetic structure of the ethnic Lao groups from mainland Southeast Asia revealed by forensic microsatellites

Srithawong

Muisuk

Srikummool

et al. 2020

Annals of Human Genetics

View full text Add to dashboard Cite

Purpose Laotians and Lao Isan are widely spread Lao groups who live in Laos and northeastern Thailand, respectively. We explored the genetic structure between them and other ethnic groups from Thailand to clarify historical patterns of admixture between Tai‐Kadai and Austroasiatic speakers, and to expand the forensic reference database for the region. Subjects and Methods We combined new genetic data for 554 individuals from 12 populations, typed for 15 autosomal short tandem repeats, with available data from 14 populations from Thailand, for a total of 1,153 raw genotypes belonging to 26 populations. We calculated forensic parameters and performed various analyses on genetic diversity, genetic structure, genetic admixture, and genetic relationships among the studied populations. Results Forensic estimators suggest a good power of discrimination with the combined power of exclusion ranging from 0.993628 to 0.999991 and a combined power of discrimination value greater than 0.99999999. Generally, the two Laotian groups were genetically similar, but the central Laotians from Vientiane have a closer genetic relationship to the Lao Isan than the northern Laotians from Luang Prabang. The Lao genetic ancestry forms the majority of the Lao Isan genetic makeup, while Austroasiatic ancestry is present at ∼10%–50%. Conclusions Lao Isan populations show signs of Lao ancestry and admixture with local Austroasiatic ancestry, which reflect historical migrations from Laos to Thailand. Lao speakers are genetically more homogeneous than Austroasiatic speakers, suggesting differential historical processes.

show abstract

Section: Discussionmentioning

confidence: 55%

Genetic structure of the ethnic Lao groups from mainland Southeast Asia revealed by forensic microsatellites

Srithawong

Muisuk

Srikummool

et al. 2020

Annals of Human Genetics

View full text Add to dashboard Cite

show abstract

“…Hardy‐Weinberg equilibrium (HWE) and linkage disequilibrium (LD) and observed heterozygosity (Ho) were estimated using Arlequin 3.5 (Excoffier et al, 2007). Pairwise Fst genetic distance between Liaoning Han and the other seven populations (Ye et al, 2017; Zhan et al, 2018) was calculated using the STRAF. Nei genetic distances between Liaoning Han and other 71 Chinese reference populations and 81 worldwide populations were estimated according to the Phylip3.695 package.…”

Section: Introductionmentioning

confidence: 99%

RETRACTED: Forensic applications and genetic characterization of Liaoning Han population revealed by extended set of autosomal STRs

Diao

Rakha

et al. 2020

Molec Gen & Gen Med

Self Cite

View full text Add to dashboard Cite

Liaoning Province is located in the North East of the People's Republic of China. In Chinese, it is known as "the Golden Triangle" because of its strategic location. Liaoning Province was established around 1907 with the name "Fengtian" and later in 1929, it was changed to Liaoning (Rhoads, 2000). The estimated population size is approximately 43.91 million with Han (83.94%) is the dominating ethnic group followed by minorities such

show abstract

“…These characteristics make STRs important for forensic DNA investigations (Hammond et al, 1994;Sánchez-Diz et al, 2009). Autosomal STRs are the most commonly used genetic markers infor forensic investigations such as paternity testing and personal identification cases (Zhan et al, 2018). Though, Ychromosomal STRs (Y-STRs) have an extra advantage in cases like sexual assault which involves mixture DNA which hascontaining predominant female DNA.…”

Section: Introductionmentioning

confidence: 99%

Phylogenetic relationship and genetic history of Central Asian Kazakhs inferred from Y-chromosome and autosomal variations

Adnan

Rakha

et al. 2019

Mol Genet Genomics

Self Cite

View full text Add to dashboard Cite

The Xinjiang Uyghur Autonomous Region of China (XUARC) with 47 ethnic groups is a most colourful ethnic region of China, harboring abundant genetic and cultural diversity, which harbors 47 ethnic groups. The Kazakhs are the third largest ethnic group (7.02%) after Uyghur (46.42%) and Han (38.99%) in Xinjiang, but their genetic diversity and forensic characterization are poorly understood. In the current study, we genotyped 15 autosomal short tandem repeat (STR) loci and 10 Y-STRs on 889 individuals (659 male and 230 female) collected from Kazak population of the Ili Kazak Autonomous Prefecture using AGCU Expressmarker 16 and 10Y-STR Kit (EX16+10Y). For autosomal STRs, we observed a total of 174 different alleles ranging from 6 and to 34.2 repeat units and FGA showed the greatest power of discrimination (20 alleles) in Ili Kazakh population. We have not observed departures from Hardy-Weinberg equilibrium (HWE) after sequential Bonferroni correction and only found a minimal departure from linkage equilibrium (LE) for a very small number of pairwise combinations of loci. The combined power of exclusion (CPE) was 0.99999998395 and combined power of discrimination (CPD) was 99.999999999999999798%. For Y-STRs, we observed a total of 496 different haplotypes on these 10 Y-STR loci. The gene diversities ranged from 0.5023 (DYS391) to 0.8357 (DYS385a/b). The overall haplotype diversity (GD) was 0.9985 with random matching probability (RMP) 0.0015. The results of population genetic analysies based on both autosomal and Y-chromosome STRs demonstrated that the genetic affinity among populations are generally consistent with exists along the ethnic, linguistic, and continental geographical classificationsboundary.

show abstract

RETRACTED ARTICLE: Forensic characterization of 15 autosomal STRs in four populations from Xinjiang, China, and genetic relationships with neighboring populations

Cited by 27 publications

References 46 publications

Genetic structure of the ethnic Lao groups from mainland Southeast Asia revealed by forensic microsatellites

Genetic structure of the ethnic Lao groups from mainland Southeast Asia revealed by forensic microsatellites

RETRACTED: Forensic applications and genetic characterization of Liaoning Han population revealed by extended set of autosomal STRs

Phylogenetic relationship and genetic history of Central Asian Kazakhs inferred from Y-chromosome and autosomal variations

Contact Info

Product

Resources

About