RETRACTED ARTICLE: Urachal tumour: case report of a poorly understood carcinoma

Scabini, Stefano; Rimini, Edoardo; Romairone, Emanuele; Scordamaglia, Renato; Vallarino, Luigi; Giasotto, Veronica; Ferro, C.; Ferrando, Valter

doi:10.1186/1477-7819-7-82

Cited by 29 publications

(27 citation statements)

References 7 publications

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“…The urachus is a vestigial musculofibrous band located between the bladder dome and umbilicus, or in the space of Retzius, which means the space between the transversalis fascia and the peritoneum 1 2. The pathogenesis of the urachal cancer has not been fully understood; however, the malignant transformation of the columnar or glandular metaplastic epithelia seems to be the cause for concern.…”

Section: Discussionmentioning

confidence: 99%

“…The pathogenesis of the urachal cancer has not been fully understood; however, the malignant transformation of the columnar or glandular metaplastic epithelia seems to be the cause for concern. Most urachal cancers are mucin-producing adenocarcinoma showing the forms of signet ring cells and an enteric-type histology that is often seen in colorectal cancer 1 3 4. The important factors in making a diagnosis with urachal cancer include the location of the lesion at the bladder dome/anterior wall, the tumour epicentre on the bladder wall, the absence of a widespread cystitis or cystic/glandularis and no other presence of primary tumours.…”

Section: Discussionmentioning

confidence: 99%

“…Urachal cancer is a rare disease, accounting for 0.01% of all the adult cancers and 0.17–0.34% of all bladder cancers 1 2. At the time of making a diagnosis, urachal cancer is usually in the progressive phase resulting in poor prognosis.…”

Section: Introductionmentioning

confidence: 99%

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Urachal cancer with direct caecal invasion: differential diagnosis from primary colon cancer

et al. 2014

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A 56-year-old man who had a history of repeated previous treatment for cystitis was admitted with abdominal distension, dysuria, pollakiuria, nocturia and sensation of urine retention after emptying the bladder. A CT scan showed a 10 cm irregularly shaped soft tissue mass abutting the anterosuperior aspect of the urinary bladder with wall thickening and a soft tissue component in the caecum. Colonoscopy revealed an encircling huge fungating mass on the caecum. The tumour was removed surgically. Histological examination showed moderately differentiated adenocarcinoma extending to the caecal wall and the bladder mucosa, the origin of the mass was consistent with that of a urachal cyst. The epicentre of the tumour was located in the bladder wall, with a distinct margin as a pathological feature. The patient was diagnosed with urachal cancer and concurrent direct caecal invasion.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Urachal cancer with direct caecal invasion: differential diagnosis from primary colon cancer

et al. 2014

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“…2 Urachus is an epithelialized tubular, fibromuscular cord between the umbilicus and the dome of the bladder that gradually narrows and becomes a fibrous band by late gestation. 4 Failure of the lumen to completely obliterate results in a persistence of urachal remnants. Although urachal remnant diseases are rare, they have been detected by USs in a majority of young patients who had non-specific abdominal or urinary symptoms, 5 and also as an incidental finding during elective surgery for umbilical hernia.…”

Section: Discussionmentioning

confidence: 99%

Ruptured remnant of urachal diverticulum: an unusual cause of congenital urinary ascites

Chilakala¹,

Boulden

Pourcyrous³

2012

J Perinatol

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Urachal diverticulum is an infrequent finding and its perforation as a cause of fetal urinary ascites has not been reported before. This is a case report on an infant with antenatal diagnosis of fetal ascites. This infant was delivered via cesarean section and needed mechanical ventilation owing to a massive ascites that required paracentesis. She did not void for 20 h until a urethral catheter was placed. The biochemical analysis of the ascitic fluid compared with the serum and urine was suggestive of urine ascites. The voiding cystourethrogram (VCUG) showed a leakage at the remnant of urachal diverticulum. The urethral catheter was maintained for 3 weeks until the repeated VCUG confirmed a sealed-off urachal diverticulum. With removal of the catheter, the infant was able to void spontaneously and was discharged home on continued prophylactic antibiotics. As symptomatic urachal remnants have an increased potential for malignant transformation, a close follow-up by a urologist was recommended.

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“…[6] All reported cases of this adenocarcinoma have been located in the intraperitoneal area, and generally developed on the anterior aspect of the bladder dome. [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16] We report the first case of a cystic non-mucinous urachal adenocarcinoma with finger-like growth in the abdominal wall.…”

Section: Introductionmentioning

confidence: 99%

A case of an abdominal wall cystic urachal carcinoma in an unusual location

Kim

Jung

Lim

et al. 2017

CRCP

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A solitary cystic lesion in the abdominal wall is generally benign, such as an omental cyst, mesenteric cyst, enteric duplication cyst, cystic mesothelioma, or skin appendage tumor. Furthermore, most malignancies in the urachal remnant are intraperitoneal lesions, and generally develop on the anterior aspect of the bladder dome. Moreover, most urachal glandular malignant neoplasms are the mucinous cystic type. We report a cystic urachal adenocarcinoma that presented as an abdominal wall cystic lesion. A 42-year-old woman was admitted to Kangwon National University Hospital for a 5-cm palpable abdominal wall mass. Conservative surgical excision was performed with subsequent histological and immunohistochemical evaluations, but only a few non-mucinous invasive glands and finger-like growths were noted. During a 2-year period, the tumor recurred several times along the urachal tract and metastasized to the regional lymph nodes. Despite receiving chemotherapy, the patient died 2 years after the first surgery.

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RETRACTED ARTICLE: Urachal tumour: case report of a poorly understood carcinoma

Cited by 29 publications

References 7 publications

Urachal cancer with direct caecal invasion: differential diagnosis from primary colon cancer

Urachal cancer with direct caecal invasion: differential diagnosis from primary colon cancer

Ruptured remnant of urachal diverticulum: an unusual cause of congenital urinary ascites

A case of an abdominal wall cystic urachal carcinoma in an unusual location

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