[Retracted] Effect of Moderate‐Intensity Aerobic Exercise on Hepatic Fat Content and Visceral Lipids in Hepatic Patients with Diabesity: A Single‐Blinded Randomised Controlled Trial

Abstract

Objective. Limited studies have assessed the effect of moderate-intensity continuous aerobic exercise on hepatic fat content and visceral lipids in hepatic patients with diabesity. is study was designed to evaluate hepatic fat content and visceral lipids following moderate-intensity continuous aerobic exercise in hepatic patients with diabesity. Design. A single-blinded randomised controlled trial. Methods. irty-one diabetic obese patients with nonalcoholic fatty liver disease were recruited into this study. e patients were randomly classified into exercise and control groups, fifteen patients in the exercise group and sixteen patients in the control group. e exercise group received an 8-week moderate-intensity continuous aerobic exercise program with standard medical treatment, while the control group received standard medical treatment without any exercise program. Hepatic fat content and visceral lipids were assessed before and after intervention at the end of the study. Results. Baseline and clinical characteristics showed a nonsignificant difference between the two groups (p > 0.05). At the end of the intervention, the aerobic exercise showed significant improvements (serum triglycerides and low-density lipoproteins (LDLs), p ≤ 0.002, total cholesterol, p � 0.004, visceral fats, p � 0.016, glycated hemoglobin (HbA1C), p � 0.022, high-density lipoproteins (HDLs), p � 0.038, alanine transaminases (AL), p � 0.044, intrahepatic triglyceride and HOMA-IR, p � 0.046, and body mass index (BMI), p � 0.047), while the control group showed a nonsignificant difference (p > 0.05). e postintervention analysis showed significant differences in favor of the aerobic exercise group (p < 0.05). Conclusions. Moderate-intensity continuous aerobic exercise reduces the hepatic fat content and visceral lipids in hepatic patients with diabesity. Recommendations should be prescribed for encouraging moderate-intensity aerobic exercise training, particularly hepatic patients with diabesity.

Effect of exercise on cardiometabolic health of adults with overweight or obesity: Focus on blood pressure, insulin resistance, and intrahepatic fat—A systematic review and meta‐analysis

“…In the single study 26 not reporting BMI values, the presence of obesity (BMI ≥ 30 kg/m 2 ) was an inclusion criteria. Males and females were present in 34 studies 18 , 21 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 57 in which the median (range) percentage of females was 59.0 (15.9–92.1)%. Eight studies included only male, 58 , 59 , 60 , 61 , 62 , 63 , 64 , 65 and 12 studies included only female adults.…”

“…In the single study 26 not reporting BMI values, the presence of obesity (BMI ≥ 30 kg/m 2 ) was an inclusion criteria. Males and females were present in 34 studies 18,21, in which the median (range) percentage of females was 59.0 (15.9-92.1)%. Eight studies included only male, [58][59][60][61][62][63][64][65] and 12 studies included only female adults.…”

“…17 In summary, a specific focus on overweight or obesity is lacking in most previous reviews and meta-analyses. Therefore, given the growing number of individuals affected by obesity-related comorbidities [18][19][20][21] and the central role of physical exercise in their management, 22 it seemed suitable to perform an update and synthesis about the effect of exercise training programs on cardiometabolic health parameters in adults with overweight or obesity. The main objective of this work is to evaluate through systematic review and meta-analysis the effect of exercise training on blood pressure values, insulin resistance, and magnetic resonance (MR) measures of intrahepatic fat in patients with overweight or obesity with or without obesity-related comorbidities.…”

Response of Inflammatory Biomarkers to 10 Weeks of Aerobic Resistance Training in Inactive Postmenopausal Women with Non-alcoholic Fatty Liver

“…The participants' weight was measured with a German digital scale (Beurer), and their waist circumference (abdominal obesity index) was measured in the narrowest area. The insulin resistance index was calculated by the following formula (19):…”

Statement of Concern

“…Additionally, a concern was raised regarding potential duplication of results in [ 1 ] that were reported in [ 2 ] and “Effect of Moderate-Intensity Aerobic Exercise on Hepatic Fat Content and Visceral Lipids in Hepatic Patients with Diabesity: A Single-Blinded Randomised Controlled Trial” [ 3 ] which appeared in Volume 2020 of Evidence-Based Complementary and Alternative Medicine . After investigation, it appears duplication did not occur as [ 1 ] presents an experimental arm (MICT), although authors appear to have failed to include deviations to experimental arms in the clinical trial registration.…”