Data analysis and interpretation, drafting the manuscript, Supervision, collection of data from patients we have tested in our office, data collection. CMD: Conception and design, critical revision of the manuscript for scientific and factual content, supervision, collection of data from patients we have tested in our office, data collection. KS: Data analysis and interpretation, conception and design, critical revision of the manuscript for scientific and factual content; drafting the manuscript, statistical analysis, collection of data from patients we have tested in our office, data collection. LMH: Data analysis and interpretation; conception and design, critical revision of the manuscript for scientific and factual content; drafting the manuscript, supervision; statistical analysis, collection of data from patients we have tested in our office, data collection.