RETRACTED: Pyoderma gangrenosum in a cesarean section wound in a woman with myelodysplastic syndrome: A case report

Abstract

Introduction Pyoderma gangrenosum and myelodysplastic syndrome in pregnant women are both very rare, but can coexist. Here, we present a case of pyoderma gangrenosum in a cesarean section wound in a woman with myelodysplastic syndrome. Case A 34-year-old woman presented with thrombocytopenia and macrocytic anemia during pregnancy. The pregnancy was uneventful until 36 weeks of gestation, when premature rupture of membranes occurred and a cesarean section was performed for breech presentation. She presented four days later with redness and blisters at the wound site. Surgical site infection was diagnosed but did not improve with antibiotics, and multiple wound cultures were negative. Skin biopsy indicated pyoderma gangrenosum, and the redness and blisters responded to oral prednisolone. Post-partum bone marrow aspiration showed myelodysplastic syndrome. As the patient demonstrated no symptoms such as abnormal bleeding, no additional treatment was started, and she went on to receive regular follow-up for myelodysplastic disorder. Discussion This case shows the need for further assessment of hematological disorders diagnosed in pregnancy in women with pyoderma gangrenosum post-partum.

Pyoderma gangrenosum following gynaecological surgery

“…The prevalence of PG worldwide is estimated to be around 3–10 cases per million individuals 2. It can occur in individuals of any age but commonly affects women aged 20–50 years 3. Most notably, PG lesions demonstrate pathergy, a phenomenon where skin trauma triggers the development of new lesions at the site of injury 4.…”

“… 2 It can occur in individuals of any age but commonly affects women aged 20–50 years. 3 Most notably, PG lesions demonstrate pathergy, a phenomenon where skin trauma triggers the development of new lesions at the site of injury. 4 The complex interplay of immunological factors and the manifestation of pathergy contribute to the diagnostic challenges of PG.…”