[Retracted] Role of Platelet‐Rich Plasma Gel in Promoting Wound Healing Based on Medical Images of Wounds

Abstract

A wound is the pathological change of soft tissue under normal skin caused by various factors, such as collision, contusion, hot crush, avulsion, corrosive chemicals, operations, excessive wound tension after operations, local pressure that cannot be relieved for a long time, liquid immersion, local infection, and rejection reactions caused by allogeneic substances. e skin itself or its underlying soft tissue loses its integrity and continuity, thus losing its normal physiological function. Medical image analysis is a medical term that refers to the interdisciplinary fields of integrated medical imaging, artificial intelligence, digital image processing and analysis, mathematical modeling, and numerical algorithms. According to the time of wound formation, they can be divided into acute and chronic wounds. e common acute wounds include lacerations caused by trauma, surgical incisions, burns, and donor sites formed after skin graft operations.is article mainly studies the role of platelet-rich plasma gel nanocomposites in promoting wound healing. It is proven that ptt-rich plasma gel can significantly promote tissue repair and regeneration and accelerate wound healing in patients with severe burns. e atomic number of the nanocomposite has a better treatment effect on the nanoparticle approach. In this paper, chitosan nanocomposite membrane, nanocomposite algorithm, and the calculation method of enthalpy of formation of high alloy nanomaterials were used to study the role of ptt-rich plasma gel combined chitosan nanocomposite membrane loaded bone marrow stromal cells in promoting wound healing, and its effects were applied to the repair of special site burns, special burns, and different age burns. Good wound repair benefits from the correct treatment of the wound, which directly affects the stability and development of the internal environment. e difference in healing time between the two groups was statistically significant, and the recovery time of the PRP group was 0.001 less than that of the control group. e results showed that the wound healing time of the PRP group was significantly shorter than that of the control group (P < 0.05); after treatment, the content of VEGF in the wound tissue of the two groups increased, especially in the PRP group; the effective rate of the PRP group was 75.0%, which was higher than 68.8% of the control group. It can play an important role in the regulation of expression and the pathophysiological process of wound healing.

A study on the preoperative risk factors for primary healing failure in the reconstruction of deep sternal wound infection with platelet‐rich plasma and negative pressure trauma therapy

“…The platelet-rich plasma (PRP) plus NPWT treatment (PRP + NPWT) is a relatively new and effective modality to treat chronic, difficult-to-heal wounds and tissue defects in recent years. [5][6][7] The authors' department also confirmed in their previous studies that this treatment modality was highly effective in treating DSWI patients, with a significant advantage over the NPWT performed alone. 8 PRP contains a small amount of plasma liquid, a few or no leukocytes, and PLTs that are higher than the average normal concentration in our blood (3 $ 10 times the normal baseline).…”

“…However, if SSWI is left to deteriorate, it would turn into DSWI which would easily affect a wound that will not heal for a long period and is difficult to treat, resulting in an elevated mortality rate. The platelet‐rich plasma (PRP) plus NPWT treatment (PRP + NPWT) is a relatively new and effective modality to treat chronic, difficult‐to‐heal wounds and tissue defects in recent years 5‐7 . The authors' department also confirmed in their previous studies that this treatment modality was highly effective in treating DSWI patients, with a significant advantage over the NPWT performed alone 8…”

Efficiency of platelet‐rich plasma in the management of burn wounds: A meta‐analysis

“…Following an assessment of 1467 pertinent examinations, 13 studies released between 2009 and 2023 were included in the meta‐analysis since they matched the criteria for inclusion 13–25 . Table 2 summarizes the findings of these investigations.…”

“…Thirteen examinations from 2009 to 2023 were enrolled for the present meta‐analysis comprising 808 people with BWs in the study's starting point: 413 of them were using PRP and 395 were using standard therapy. The sample size was 25 to 100 subjects 13–25 . The examined data revealed that PRP had a significantly shorter healing time, a higher healing rate, a higher healed area percent and a higher graft take area percent compared with standard therapy in patients with BW.…”

“…The sample size was 25 to 100 subjects. [13][14][15][16][17][18][19][20][21][22][23][24][25] The examined data revealed that PRP had a significantly shorter healing time, a higher healing rate, a higher healed area percent and a higher graft take area percent compared with standard therapy in patients with BW. However, no significant difference was found between PRP and standard…”