Many ancient libraries in Italy are housed in historical buildings, only a few in former churches and monasteries. Newly built libraries mostly comply with the requirements of sustainability, energy saving and renewable energy use, but this does not occur for existing ones, especially when they belong to the historical cultural heritage. Historical library buildings have good mass and thermal inertia but often have inadequate windows with low light transmission value. Lighting systems are often without control and thus cause poor lighting conditions. Our present research concerns the energy sustainability assessment of retrofit operations for lighting in an existing historical university library, focusing on lighting quality, adequate lighting conditions for visual tasks, vision ergonomics and well-being, and guaranteeing the preventive conservation and protection of heritage books. This case study is very particular, because it concerns a Florentine historical monastery which is now a university library. Our proposed method introduces an optimal toolset for lighting design solutions with the aim of sustainability. The library indoor space was procedurally decomposed into illumination volumes according to different occupant activities and visual tasks and different use areas. This method is extensible to all similar cultural heritage case, but also existing old buildings and current designs. Sustainability 2019, 11, 3145 2 of 17Today, libraries are conceived and designed as spaces that are more virtual than physical, whether they are part of recovery and retrofitting interventions or new projects: their use, reading and research practices have been transformed and, at the same time, almost all the users have replaced notebooks with laptops, occupying a larger reading station than in the past; while at the PC station, it is also possible to consult a wide variety of texts necessary for study and research. Nowadays, libraries are also an integrated service system.Of all the libraries in Italy, approximately 50% are subjected to certain limits and over 90% are grade listed [7][8][9]. Most of them were built prior to 1930. Almost all of them are totally inefficient from energy and environmental points of view [7][8][9]. Several European programs have highlighted and aimed at integrating the recommendations of the Efficiency Performance Building Directives, EPBD and EPBD2 [10,11], European Committee for Standardization (French: Comité Européèn de Normalisation, CEN [12]), then of CEN TC 346 [13] and of the EnerPHit Certified Retrofit (PHI) in historic buildings [14]. The guidelines of the Ministry of Cultural Heritage and Activities (in Italian: Ministero per i Beni e le Attività Culturali, MiBAC) on the energy efficiency of the historical heritage are very important and decisive [15]. There are significant examples of recent European projects in the field of the redevelopment of historic buildings, which were designed and financed for the application of the aforementioned directives, such as the 2009 European project...