Retrolaminar Migration of Intraocular Silicone Oil

Abstract

Greater awareness on the part of treating physicians, systematic study of at-risk populations, and advances in imaging technology will allow further insight into this phenomenon.

Orbital, eyelid, and nasopharyngeal silicone oil granuloma presenting as ptosis & pseudo-xanthelasma

“… 7 Intracranial migration of silicone without optic pits has also been reported in the literature. 16 …”

Subretinal and Retrolaminar Migration of Intraocular Silicone Oil Detected on CT

“…Retrolaminar SiO migration is believed to be a benign phenomenon usually detected incidentally on cross-sectional imaging. 5 However, visual symptoms have been reported and are thought to be related to silicone-induced optic neuropathy secondary to macrophage infiltration. 9,26,27 In our series, no significant neuro-ophthalmologic or neurologic complications related to SiO migration have been documented in the medical records.…”

“…3,4 Retrolaminar SiO migration is a lesser known complication of intraocular SiO injections, occurring when the SiO diffuses posteriorly into the optic apparatus (optic nerve, chiasm, and tract) and potentially into the subarachnoid space and ventricular system. [5][6][7] Vision loss due to optic neuropathy has been reported as a consequence of this posterior migration. 8 Although several histologic and immunohistopathologic studies have demonstrated SiO migration in the ophthalmologic literature, 6,9 data about the prevalence and/or radiologic findings of SiO migration are limited.…”

“…8 Although several histologic and immunohistopathologic studies have demonstrated SiO migration in the ophthalmologic literature, 6,9 data about the prevalence and/or radiologic findings of SiO migration are limited. 5,[10][11][12][13][14][15][16][17][18][19][20][21] The purpose of this study was to document the prevalence of retrolaminar migration of intraocular SiO on head CT and describe the clinical and radiologic findings.…”

Migración intracraneal de aceite de silicona a través del nervio óptico post-vitrectomía

“…La migración intracraneal del aceite de silicona intraocular es una rara complicación en el tratamiento de la retinopatía diabética 1 . Desde el punto de vista neurológico, la historia natural de la migración de la silicona parece benigna en la mayoría de los casos; muchos se detectaron incidentalmente durante la evaluación de síntomas inespecíficos, como dolores de cabeza o mareos 5 . Se han postulado varios posibles mecanismos etiopatogénicos para explicar este fenómeno de migración que incluyen: una copa óptica profunda o depresiones congénitas en el nervio óptico que facilitarían la migración del aceite de silicona al espacio subaracnoideo a través de la piamadre, la fagocitosis por macrófagos del aceite de silicona o la degeneración cavernomatosa del nervio óptico por un aumento de la presión intraocular que permitiría el paso del aceite de silicona al espacio subaracnoideo 1 .…”