Retroperitoneal fibrosis: A two decade experience and gynecologic manifestations

Abstract

A 20-year experience with idiopathic retroperitoneal fibrosis (RPF) is presented (6 cases). Its gynecologic manifestations with the simulation of pelvic malignancy is discussed. Three of the patients presented with pelvic masses, one of these a para-vaginal mass. In one patient, RPF followed or was concurrent with invasive squamous cell carcinoma of the cervix, of which this is the first reported case. The subject of RPF is reviewed with the modes of management and evidence for an autoimmune etiology. Thrombocytopenia, a previously unreported finding with RPF, was noted in three of the six patients. The reversal of the A/G ratio in these patients is discussed, correlating this finding with the progression of azotemia.

Retroperitoneal Fibrosis Mimicking Prostate Cancer

“…Quinidine was promoted by Thomas Lewis for the termination and prevention of atrial fibrillation, 1 after Karel Wenckebach had shown in 1914 that the related drug quinine could halt paroxysms of this arrhythmia. 2 In 1951 Maurice Sokolow reported conversion to normal rhythm with no important side-effects in 80% of 111 personal cases of atrial fibrillation and flutter, using blood level control.…”

“…the priorities are to restore adequate ventilation and obtain a pathological diagnosis. 1 The choice of bronchoscopic techniques includes Nd-YAG laser, diathermy and cryotherapy, 2 all of which carry a risk of bleeding. Thereafter, complete resection with primary reconstruction of the airways offers the best chance of cure.…”

Retroperitoneal fibrosis mimicking prostate cancer

“…2 In 1951 Maurice Sokolow reported conversion to normal rhythm with no important side-effects in 80% of 111 personal cases of atrial fibrillation and flutter, using blood level control.…”

“…1 The choice of bronchoscopic techniques includes Nd-YAG laser, diathermy and cryotherapy, 2 all of which carry a risk of bleeding. Thereafter, complete resection with primary reconstruction of the airways offers the best chance of cure.…”