Retroperitoneal malignant mesenchymoma: imaging findings in five cases

Suzuki, Shigeru; Furui, Shigeru; Kokubo, T; Moriyama, Noriyuki; Kohtake, Hiroshi; Takeshita, Koji; Harasawa, Arimi; Sasaki, Yuzo; Yamauchi, Takayoshi; Shirai, Tsuguru; Ban, Sadahiko; Kikuchi, Yoshirou

doi:10.1007/s002619900449

Cited by 10 publications

(6 citation statements)

References 11 publications

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“…The massive calcification we found corresponded to an osteosarcomatous component, while the non-calcified enhancing nodules were, respectively, consistent with leiomyosarcoma, liposarcoma, and fibrosarcoma. A well-differentiated liposarcomatous component can have a fatty component (5), though in our case none was apparent at CT. The composition of a malignant mesenchymoma - whether or not it contains calcification or ossification, a fatty component, or necrotic soft tissue - seems to determine its radiological features.…”

Section: Discussioncontrasting

confidence: 63%

“…Although none were common to all the cases they described, Suzuki et al (5) suggested that the typical findings of malignant mesenchymoma were large tumor size, a sharp margin, heterogeneous make-up, and massive calcification. The tumor in our case was also a huge heterogeneous mass with massive intratumorous calcification, but a feature different from those previously noted was also present.…”

Section: Discussionmentioning

confidence: 97%

“…Despite the publication of several cases reports involving a small series (2-5), the varying composition of tumors and the small number of reported cases has led to a lack of widespread awareness of the related radiological findings. We report a rare case of primary retroperitoneal malignant mesenchymoma showing distinctive radiological findings.…”

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confidence: 99%

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Retroperitoneal Malignant Mesenchymoma: A Case of Mesenchymal Mixed Tumor with Osteosarcoma, Leiomyosarcoma, Liposarcoma and Fibrosarcoma

et al. 2002

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Malignant mesenchymoma is an interesting but very rare tumor in which malignant differentiation has occurred twice or more. We report a case of retroperitoneal malignant mesenchymoma consisting of osteosarcoma, leiomyosarcoma, liposarcoma and fibrosarcoma. Abdominal CT showed a large retroperitoneal mass with two separate and distinct parts, namely an area of prominent calcification and one of clearly enhancing solid components. The mass contained histologically distinct tumorous components with no histologic admixure at the interfaces. The densely calcified nodule corresponded to osteosarcoma, and the non-calcified clearly enhancing nodules to leiomyosarcoma, liposarcoma and fibrosarcoma.

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Section: Discussioncontrasting

confidence: 63%

Section: Discussionmentioning

confidence: 97%

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Retroperitoneal Malignant Mesenchymoma: A Case of Mesenchymal Mixed Tumor with Osteosarcoma, Leiomyosarcoma, Liposarcoma and Fibrosarcoma

et al. 2002

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“…The radiologic findings of well-circumscribed and heterogeneous mass which, including osteosarcomatous components, were considered to be MMs. [ 8 ] In our case, tumor was a homogeneous mass and without calcification. It was hard to determine malignant character although the biopsy was done before operation.…”

Section: Discussionmentioning

confidence: 61%

Primary malignant mesenchymoma of bladder

Yang

et al. 2017

Medicine

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Rationale:Malignant mesenchymoma (MM) is defined as a heterogeneous malignant soft tissue tumor that consists of 2 or more distinctly different mesenchymal components in addition to fibrosarcomatous elements. Bladder MM was rarely reported in the literature and there are only 5 cases of primary bladder MM documented in English literature to date.Patient concerns:A 58-year-old male complained of difficulty in urination and intermittent gross hematuria for 3 months. Doppler ultrasound scan revealed an avascular and homogeneous hypoechoic mass measured 6.5 × 9 cm in the bladder. Computed tomography showed a homogeneous solid mass in the bladder.Diagnoses:Pathology revealed spindle-shaped tumor and proliferation of poorly differentiated immature mesenchymal cells rich in eosinophilic cytoplasm with hyperchromatic sticklike nuclei. Immunohistochemical examinations were positive for CD117.Interventions:The patient was diagnosed with presence of bladder tumor and underwent radical cystectomy; the optimal treatment strategy was reviewed and discussed.Outcomes:There was no recurrence or metastasis during a 16-month follow-up.Lessons:Our case study demonstrated bladder MM with a relatively indolent clinical course. A multidisciplinary approach including surgery, radiotherapy, and chemotherapy may be useful. Radical resection is the most important determinant of clinical outcome. Generally, the clinical outcome and prognosis of mesenchymoma are favorable.

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“…25 It has been postulated that this tumor could arise from primitive and uncommitted mesenchymal cells that differentiate along multiple cell lines. 8,16 Various authors have postulated a relationship between trauma and scar formation in the development of mesenchymoma in humans 24 and dogs.…”

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confidence: 99%

An Intra-Abdominal Malignant Mesenchymoma Associated with Nonabsorbable Sutures in a Ferret (Mustela Putorius Furo)

Petterino

Bedin²,

Vascellari

et al. 2010

J VET Diagn Invest

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Abstract. A 6-year-old ferret (Mustela putorius furo) was presented with abdominal enlargement. Clinical examination revealed an intra-abdominal mass measuring approximately 5 cm in diameter. Abdominal survey radiographs revealed a sharply marginated mass with multifocal radiodense foci, suggestive of pathologic calcification. A complete blood cell count revealed a moderate, normocytic, normochromic, nonregenerative anemia. The mass was surgically removed en bloc, fixed in 10% neutral buffered formalin solution, and routinely processed for histologic and immunohistochemical investigation. The neoplastic tissue consisted of a mixed neoplastic cell population, including osteosarcoma and fibrosarcoma components. Immunohistochemistry revealed that both neoplastic cell populations were positive for vimentin and negative for actin (smooth and striated), desmin, and myoglobin. Nonabsorbable suture material was admixed with the neoplastic tissue in the histologic section. This material was birefringent when viewed microscopically under polarized light.

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Retroperitoneal malignant mesenchymoma: imaging findings in five cases

Abstract: The radiologic findings of large expansile heterogeneous masses in the retroperitoneum, especially with massive calcifications, were considered to be typical of malignant mesenchymomas.

Cited by 10 publications

References 11 publications

Retroperitoneal Malignant Mesenchymoma: A Case of Mesenchymal Mixed Tumor with Osteosarcoma, Leiomyosarcoma, Liposarcoma and Fibrosarcoma

Retroperitoneal Malignant Mesenchymoma: A Case of Mesenchymal Mixed Tumor with Osteosarcoma, Leiomyosarcoma, Liposarcoma and Fibrosarcoma

Primary malignant mesenchymoma of bladder

An Intra-Abdominal Malignant Mesenchymoma Associated with Nonabsorbable Sutures in a Ferret (Mustela Putorius Furo)

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