Retroperitoneal malignant schwannoma in a child

Abstract

Retroperitoneal malignant schwannomas are extremely rare. Only a few cases have been reported, only one of which occurred in a child. We herein report a case of retroperitoneal malignant schwannoma in a 2-year-old boy who presented with a painless mass in the right lumbar region. The mass had gradually enlarged during a 1-year period, and it was about the size of the patient’s fist at the time of consultation. Whole-abdomen computed tomography revealed a space-occupying lesion in the retroperitoneum infiltrating from the L1 to L4 spinal canal. A preoperative diagnosis of a retroperitoneal tumor was made, and complete tumorectomy was performed. Postoperative pathological examination showed a malignant schwannoma. The tumor recurred 1 month after the first operation, and a second complete excision was carried out; the postoperative pathologic examination findings were similar to the previous findings. The patient recovered well and continued to undergo close follow-up.

Pelvic schwannoma in an adult male

“…In a recent report, Xu Hao et al 9 reported a successful removal of 16-cm retroperitoneal schwannoma in an elderly patient; however, the evidence of excessive bleeding was seen in this case. Similarly, in a recent report by Wang Yun et al, 10 a pediatric case of a painless schwannoma near the right lumbar region was presented; however, after successful removal of the tumor, one month later, recurrence was seen. A schwannoma can often be removed without associated deficits, and the nerve axons are not disrupted in the course of the procedure.…”

Clinical Characteristics and Treatment Strategy of Retroperitoneal Schwannoma Adjacent to Important Abdominal Vessels: Three Case Reports and Literature Review

“…Because of its insensitivity to radiation and chemotherapy, re-surgical resection is recommended for recurrent schwannoma ( 28 ). Malignant schwannomas have a poor prognosis and a high recurrence rate, so early diagnosis is important while emphasizing the necessity of close postoperative follow-up ( 29 ). We should know that regardless of the nature of the tumor, the difficulty of surgery is closely related to the size of the mass and adjacent adhesions, so the importance of early surgery is emphasized instead of only considering the surgical technique ( 30 ).…”

Peripheral nerve sheath malignancy with multiple metastasis: a rare clinical case

“…Учитывая тот факт, что в клинике продолжительность онкозаболевания составила около 1 года 8 месяцев, сопровождалось продолженным инфильтративным ростом неоплазии в костный мозг, развитием гематогенных метастазов в различные органы, плохо поддавалась хирургическому и химиотерапевтическому воздействию, можно полагать, что данное злокачественное новообразование имело высокоагрессивный потенциал, склонный к гематогенной диссеминации. Вероятно, данная опухоль могла возникнуть из шванномы [2,8], о чем указывают сведения из истории болезни.…”

“…В доступной нам современной отечественной и зарубежной литературе имеются немногочи-КЛИНИЧЕСКИЕ СЛУЧАИ / CLINICAL CASES сленные описания отдельных клинических наблюдений злокачественной опухоли оболочек периферического нерва параспинальной локализации, тем более при развитии метастатического каскада [4,5,7,8,10,15].…”

“…В отдельных клинических работах у 20-25% пациентов описаны метастазы ЗОПН в легкие [6,7]. В современной литературе имеются немногочисленные публикации клинических наблюдений ЗОПН, в то время как описания секционных случаев единичны [8,9].…”