Retrospective Analysis of Negative Pressure Wound Therapy in Open Foot Wounds with Significant Soft Tissue Defects

Page, Jeffrey C.; Newswander, Brad; Schwenke, Dawn C.; Hansen, Myron; Ferguson, John C.

doi:10.1097/00129334-200409000-00015

Cited by 42 publications

(31 citation statements)

References 27 publications

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“…Wound closure (secondary healing or surgical closure) was described as the incidence of complete wound closure in 2 studies 20,22 and as the time to wound closure (complete or incomplete) in 7 studies 23,[26][27][28]31,36,37 (Table 3). Only 2 of the 5 RCTs 20,26 and 2 of the 4 non-RCTs 28,37 reported a significant advantage in favor of NPWT.…”

Section: Clinical Resultsmentioning

confidence: 99%

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Negative Pressure Wound Therapy

Gregor

Maegele²,

Sauerland³

et al. 2008

Arch Surg

163

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Section: Clinical Resultsmentioning

confidence: 99%

“…Hospital stay was shortened by NPWT in 1 non-RCT 28 but was similar in 4 other nonRCTs. 31,32,34,35 An economic analysis was performed in 1 RCT, 24 yielding similar overall costs for NPWT and conventional therapy.…”

Section: Clinical Resultsmentioning

confidence: 99%

Negative Pressure Wound Therapy

Gregor

Maegele²,

Sauerland³

et al. 2008

Arch Surg

163

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“…The extensive studies on the established use of the VAC technique in the wound-healing phase of granulation have resulted in guidelines that recommend VAC therapy in acute and chronic wounds [7,8,9,10,11,12], burns [13], diabetic ulcers [14, 15] as well as open foot wounds [16], vasculitis- or occluding vasculopathy-induced ulcers [17]. However, there have been very few reports on the postoperative application of VAC therapy [18, 19].…”

Section: Discussionmentioning

confidence: 99%

Vacuum Assisted Closure Device Improves the Take of Mesh Grafts in Chronic Leg Ulcer Patients

et al. 2008

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Background: Vacuum assisted closure (VAC) is established in the management of acute and chronic wounds. In recent years, few data have been published concerning VAC therapy after skin graft transplantation. Objectives: The aim of this study was to determine whether postoperative VAC helps assist closure of mesh grafts in chronic leg ulcer patients. Patients/Methods: We report a consecutive case series of 54 patients with chronic leg ulcers who received a total of 74 mesh grafts. A postoperative VAC therapy was performed in 28 mesh grafts, and 46 mesh grafts were treated with standard gauze therapy. Results: In the VAC group, 92.9% of grafts showed complete healing, compared to 67.4% in the control group without postoperative VAC therapy. Differential analysis revealed a negative correlation of the take rate in patients over 70 years of age or in patients suffering from diabetes mellitus or dermatoliposclerosis. Particularly patients with diabetes mellitus and of greater age exhibited improved take rates, both 100%, in the VAC group compared to 50 and 62%, respectively. Conclusion: The results of our retrospective study demonstrate for the first time the significant benefit of VAC therapy after skin grafting in chronic leg ulcer patients as evaluated in a clinical trial.

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“…Treatment with NPWT, allowed these patients to be discharged from hospital and treated at home, where they could maintain greater mobility with improved quality of life. Within home healthcare settings, Page et al (2004) reported that NPWT may help to improve patient care…”

Section: Use Of Npwt In Primary Secondary and Acute Settingsmentioning

confidence: 99%

Negative pressure wound therapy in the community: the debate

Ousey

Milne

2009

Br J Community Nurs

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Recent government documents (Department of Health 2009) have suggested that as a result of advances in tissue viability, more complex wound care can now be provided in the community setting and that therapies such as Negative Pressure Wound Therapy [NPWT] should be common place with tissue viability professionals appointed to direct service provision and ensure high standards (DH 2009). This is a major step forward in current thinking however there are still gaps in our understanding of NPWT with regard to both the mechanism of action and which wound types will respond most favourably to the therapy.Managing complex patients in the community setting can be challenging add to this scenario a device that has to remain attached for around 22 out of 24 hours a day certainly brings new challenges. It yet remains to be ascertained if it is appropriate for all patients or if some definitive exclusion criteria should be agreed. This paper will seek to explore the mechanism of action, benefits, and barriers to adoption in community settings.

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Retrospective Analysis of Negative Pressure Wound Therapy in Open Foot Wounds with Significant Soft Tissue Defects

Cited by 42 publications

References 27 publications

Negative Pressure Wound Therapy

Negative Pressure Wound Therapy

Vacuum Assisted Closure Device Improves the Take of Mesh Grafts in Chronic Leg Ulcer Patients

Negative pressure wound therapy in the community: the debate

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