Retrospective analysis of paediatric glaucoma at a tertiary referral centre in Hong Kong

Chan, Jonathan C.H.; Chow, Shing Chuen; Lai, Jimmy Shiu Ming

doi:10.1007/s10384-020-00779-4

Cited by 8 publications

(11 citation statements)

References 37 publications

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“…Conversely, many studies have reported a higher prevalence of secondary glaucoma than PCG. The prevalence of PCG in Hong Kong and Thailand was similar to the 17% reported in the USA and was much lower than in our studies (12,16). The number of boys was more than twice that of girls in this study, which is consistent with reports from northern China, the United States, and Europe (20,21).…”

Section: Discussionsupporting

confidence: 90%

“…This could be related to the different medical referral systems. The number of male pediatric patients was higher than that of female patients (63.60% vs. 36.40%; 1.75:1), which is similar to previously published results (12)(13)(14)(15)(16). Moreover, 8.79% of patients in this study had a family history of glaucoma, which was slightly higher than in studies conducted in eastern China and parts of Asia, including Thailand (12,13).…”

Section: Discussionsupporting

confidence: 87%

“…AGV was treated for multiple surgical failures or secondary pediatric glaucoma in this study. In Hong Kong, the most common surgical intervention is AGV (16). Similar to the Hong Kong report, we observed that patients with aniridia accepted AGV as the primary treatment in central China (16).…”

Section: Discussionsupporting

confidence: 83%

“…PCG was the most prevalent type of glaucoma in this study population, and it was present in 55.43% of the patients. Many studies have reported varied distributions of subtypes of pediatric glaucoma (5,7,8,13,16,19). Similar results were observed in mainland reports from Chinese populations of Beijing Tongren Hospital and Shanghai Eye, Ear, Nose and Throat Hospital (13,14).…”

Section: Discussionsupporting

confidence: 76%

“…The clinical parameters of the different types of glaucoma are described in Table 5. In all patients, the IOP decreased to 16…”

Section: Follow-up Findings Of Patients With Pediatric Glaucomamentioning

confidence: 86%

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Clinical Analysis of Pediatric Glaucoma in Central China

Liu

et al. 2022

Front. Med.

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PurposeWe aimed to describe the characteristics, epidemiology, management, and outcomes of glaucoma in pediatric patients in central China.MethodsThis study retrospectively analyzed inpatients with pediatric glaucoma at Henan Provincial People's Hospital, Henan Eye Institute, and Henan Eye Hospital between 2017 and 2020.ResultsOverall, 239 cases (276 eyes) of pediatric glaucoma in patients, comprising 87 girls (36.40%) and 152 boys (63.60%) were analyzed. The mean age was 6.65 ± 4.46, and 2.93% of the patients had a family history of glaucoma. Primary congenital glaucoma (PCG) was the most common type of glaucoma, followed by traumatic glaucoma in 8.33% of the patients, which was considered secondary glaucoma. The most common signs and symptoms were elevated intraocular pressure (IOP) and eye pain. Trabeculotomy (Trab) and microcatheter-assisted 360° trabeculotomy (MAT) combined with Trab were the most commonly performed surgeries. The IOP of patients with PCG, juvenile open-angle glaucoma (JOAG), and secondary glaucoma were 15.27 ± 7.48 mmHg, 17.16 ± 10.05, and 18.65 ± 8.55, respectively, at the final follow up. The rate of re-operations in patients with PCG, JOAG, and secondary glaucoma were 9.15%, 6.78%, and 4.69%, respectively. The mean visual acuity of the eyes with PCG, JOAG, and secondary glaucoma was 0.79 ± 0.68, 0.51 ± 0.48, and 0.53 ± 0.50, respectively.ConclusionPCG, JOAG, and traumatic glaucoma were the most prevalent subtypes in patients with pediatric glaucoma in central China. Trab and MAT combined with Trab were the most common interventions used in this study. Pediatric amblyopia might require full attention during the entire treatment, especially after glaucoma surgery. Effective preventive measures and more public education on glaucoma prevention and the importance of early diagnosis and treatment is necessary.

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Section: Discussionsupporting

confidence: 90%