Retrospective analysis of the treatment of melasma lesions exhibiting increased vascularity with the 595‐nm pulsed dye laser combined with the 1927‐nm fractional low‐powered diode laser

Geddes, Elizabeth R.; Stout, Ashlyn B.; Friedman, Paul M.

doi:10.1002/lsm.22518

Cited by 34 publications

(35 citation statements)

References 12 publications

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“…24,27 Moreover, long-term remission is particularity difficult in patients with melasma due to the potential side effects of long-pulsed or QSNL systems. 19,27,28 Recent studies, therefore, have focused on treatments using laser systems that target cutaneous vasculature 29,30 or energy-based devices 9,31 to increase the success rate and rate of clinical improvements.…”

Section: Discussionmentioning

confidence: 99%

Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q‐switched 1064‐nm Nd:YAG laser for treatment of environment‐induced skin pigmentation

Kim

Lee

et al. 2020

J of Cosmetic Dermatology

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Background Extrinsic skin aging caused by atmospheric pollutants is associated with a sustained inflammatory response which is a significant risk factor for lentigines and melasma. Aims The aim of this study was to evaluate the efficacy of topical application of combination formulation of vitamin C, vitamin E, and ferulic acid as an adjuvant to Q‐switched Nd:YAG (QSNY) lasers treatment in individuals with lentigines and melasma. Methods A single blinded, prospective, randomized split‐face trial was conducted. Eighteen men and women between 26 and 53 years old were treated with a combination antioxidant serum on one randomized side of their face immediately after QSNY laser and twice daily for 2 weeks. Patients were evaluated using digital photography and spectrometry to assess the melanin index and erythema index. Melasma severity score and global improvement scores also were assessed. Results The treated side of the face exhibited a significantly greater reduction in the melanin index. There was no significant difference in post‐treatment erythema. More clinical improvement was observed on the treated side compared with the untreated side. Conclusions Our study suggests that topical application of a combination vitamins C, E, and ferulic acid antioxidant formula may be effective as an adjuvant option in QSNY lasers.

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Section: Discussionmentioning

confidence: 99%

Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q‐switched 1064‐nm Nd:YAG laser for treatment of environment‐induced skin pigmentation

Kim

Lee

et al. 2020

J of Cosmetic Dermatology

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“…As a hypothesis, rather than considering the thermal relaxation time or stress relaxation time of the vasculature, we might additionally suggest that it is the picosecond domain‐related photomechanical effect on the endothelium of the target vessels, coupled with the selective absorption of the 595 nm energy in the erythrocytes, which could be affecting the overproduction of endothelial adhesion molecules from the hyperactive microvasculature. This could in turn influence the intracellular adhesion molecule signaling from the fibroblasts to the keratinocytes, thus breaking the inflammatory cycle and reducing the melanin‐stimulating hormone effect on the lesional melanocytes . This is an attractive hypothesis, but requires further immunohistochemical study to establish proof.…”

Section: Discussionmentioning

confidence: 99%

Efficacy and safety of a novel picosecond laser using combination of 1 064 and 595 nm on patients with melasma: A prospective, randomized, multicenter, split‐face, 2% hydroquinone cream‐controlled clinical trial

et al. 2017

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A 750 picosecond laser using 1 064 and 595 nm was effective and safe for the treatment of Korean melasma patients. The picosecond laser with dual-wavelength used in this study can reduce the photothermal effect generated during the removal of pigment and total duration of the procedure, and can be expected to reduce the occurrence of adverse events. Lasers Surg. Med. 49:899-907, 2017. © 2017 Wiley Periodicals, Inc.

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“…However, some PIH was reported along with relatively frequent relapses. Interestingly, a recent retrospective study that used thulium laser and PDL showed an improvement superior to 50% in six of the 11 patients without any PIH or rebound . Prospective randomized comparative trials are still required to determine the usefulness of this device for treating melasma.…”

Section: Clinical Indicationsmentioning

confidence: 99%

“…Interestingly, a recent retrospective study that used thulium laser and PDL showed an improvement superior to 50% in six of the 11 patients without any PIH or rebound. 161 Prospective randomized comparative trials are still required to determine the usefulness of this device for treating melasma. Ablative fractional lasers can also be used for enhancing the penetration and efficacy of HQ.…”

Section: Recommendationmentioning

confidence: 99%

Laser treatment of hyperpigmented lesions: position statement of the European Society of Laser in Dermatology

Passeron

Genedy

Salah

et al. 2019

Acad Dermatol Venereol

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Background Lasers and intense pulsed light sources (IPLS) are proposed for the treatment of many pigmentary disorders. They are sometimes considered as magic tools able to remove any type of lesions. Although being the best option for several hyperpigmented lesions, they can also worsen some conditions and have potential side‐effects. Objective The aim of this review was to give evidence‐based recommendations for the use of lasers and IPLS in the treatment of hyperpigmented lesions. Methods These recommendations were produced for the European Society of Laser Dermatology by a consensus panel made up of experts in the field of pigment laser surgery. Recommendations on the use of lasers and light treatments were made based on the quality of evidence for efficacy, safety, tolerability, cosmetic outcome, patient satisfaction/preference and, where appropriate, on the experts' opinion. Results Lasers and IPLS are very effective for treating many hyperpigmented lesions such as lentigos, dermal hypermelanocytosis or heavy metal depositions. In the other hand, they have to be considered with great caution for other disorders, such as café au lait macules, melasma or postinflammatory hyperpigmentation. After making the correct diagnosis, if lasers or IPLS are indicated, the optimal wavelengths and parameters will be chosen taking into account the skin phototype, origin and depth of the target pigments. Conclusion Although potentially very effective, lasers and IPLS cannot be proposed for all types of hyperpigmented lesions. In all cases, precise recognition of the disorder is mandatory for choosing between these devices and other therapeutic approaches.

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Retrospective analysis of the treatment of melasma lesions exhibiting increased vascularity with the 595‐nm pulsed dye laser combined with the 1927‐nm fractional low‐powered diode laser

Cited by 34 publications

References 12 publications

Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q‐switched 1064‐nm Nd:YAG laser for treatment of environment‐induced skin pigmentation

Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q‐switched 1064‐nm Nd:YAG laser for treatment of environment‐induced skin pigmentation

Efficacy and safety of a novel picosecond laser using combination of 1 064 and 595 nm on patients with melasma: A prospective, randomized, multicenter, split‐face, 2% hydroquinone cream‐controlled clinical trial

Laser treatment of hyperpigmented lesions: position statement of the European Society of Laser in Dermatology

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