Retrospective analysis of vivax malaria patients presenting to tertiary referral centre of Uttarakhand

Srivastava, Saurabh; Ahmad, Sohaib; Shirazi, Nadia; Verma, Shilp; Puri, Prashant

doi:10.1016/j.actatropica.2010.10.001

Cited by 35 publications

(23 citation statements)

References 19 publications

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“…vivax malaria. (19,20) Studies from Qatar and Venezuela had shown the similar results. (21,22) There is no matched control group.…”

Section: Discussionsupporting

confidence: 69%

Correlation of Type of Species and Parasite Density in Malaria With Platelet Count, Mean Platelet Volume and Platelet Distribution Width

Kumar¹

2016

jemds

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BACKGROUNDMalaria is an important infectious protozoan disease and it has been estimated that worldwide there are 300 -500 million cases of malaria per year and 1.5 -2.7 million deaths. The early diagnosis of malaria is the key feature for its prompt treatment and prevention of complications. The study was conducted to statistically analyse other haematological parameters like platelet indices that is Mean Platelet Volume (MPV) and Platelet Distribution Width (PDW) along with platelet count. Correlation of the above was done with parasite density and type of species. An attempt was made to study whether platelet indices and counts are indicative of type of infection.

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“…vivax malaria. (19,20) Studies from Qatar and Venezuela had shown the similar results. (21,22) There is no matched control group.…”

Section: Discussionsupporting

confidence: 69%

Correlation of Type of Species and Parasite Density in Malaria With Platelet Count, Mean Platelet Volume and Platelet Distribution Width

Kumar¹

2016

jemds

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“…The P.vivax (67%) was found predominantly. This is supported by other studies where P. vivax was predominantly detected [14][15][16] . Some studies show P.falciprum being predominant malarial parasite [17][18] .…”

Section: Discussionsupporting

confidence: 80%

Untitled

2016

IJPSR

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Background: Malaria is a serious parasitic health problem in India. Plasmodium vivax and falciparum pose the greatest public challenge in endemic areas. P. vivax accounts for more than half of all malaria cases. Accurate and prompt diagnosis is not only important to prevent morbidity, but also helps minimizing drug resistance. Aim: To know the profile of malaria parasite in the patients attending UPRIMS&R, a tertiary care center in Western Uttar Pradesh. Methods: A total 26,939 samples were subjected to smear microscopy (thin and thick) or rapid diagnostic tests. Result: 1330 positive malaria cases were detected. Malaria cases were maximum in year 2010. The proportion of P.vivax, P.falciprum and mixed malaria parasites was found 67% (891 out of 1330), 32% (420 out of 1330) and 1% (19 out of 1330) respectively. Conclusion: There is a decline in trend of malaria cases in India. The highest load of malaria cases was found in month September. P. vivax is still a predominant malaria parasite.

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“…In addition, there are a number of case series and retrospective data on severe vivax malaria among adults and children that have been reported from other parts of North India. [6][7][8] In a large study of 91 patients from Pakistan with severe malaria, 9 P. vivax contributed to 11% (9/91) of cases. Severe anaemia was present in 42% of their patients, consistent with our findings [severe anaemia: 37.1% (13/35)].…”

Section: Discussionmentioning

confidence: 99%

Clinical spectrum and treatment outcome of severe malaria caused byPlasmodium vivaxin 18 children from northern India

Gehlawat

Arya

Kaushik

et al. 2013

Pathogens and Global Health

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Objective: The study was intended to document the clinical profile and treatment outcome of severe malaria caused by Plasmodium vivax (P.vivax) in children hospitalized in a tertiary care centre of northern India. Methods: This prospective observational study was performed among children admitted with severe malaria at a tertiary care referral hospital of northern India from January 2012 to December 2012. Information was recorded pertaining to clinical symptoms at presentation, examination findings, biochemical and hematological investigation, and treatment outcome. Presence of malarial parasite on thick and thin smears and/or positive parasite lactate dehydrogenase (p-LDH) based rapid malaria antigen test was considered diagnostic of 'malaria'. Based on the etiology, children were categorized into three groups: P.vivax, Plasmodium falciparum (P. falciparum) and mixed infection. Children diagnosed with 'severe malaria' (World Health Organization, 2000), were started on intravenous artesunate followed by artemether-lumefantrine combination. . Two children [2/18 (11.1%)] infected with P. vivax had died of cerebral malaria, acute respiratory distress syndrome, shock, and metabolic acidosis. The clinical presentation and outcome of severe vivax malaria was found to be similar to severe malaria caused by P. falciparum and mixed infection, except for higher chances of severe anaemia among the children infected with P. falciparum (P50.04). Conclusion: The present study highlights P. vivax as an increasingly recognized causative agent for severe malaria in children from Rohtak, with similar clinical presentation and outcome to that caused by P. falciparum.

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Retrospective analysis of vivax malaria patients presenting to tertiary referral centre of Uttarakhand

Cited by 35 publications

References 19 publications

Correlation of Type of Species and Parasite Density in Malaria With Platelet Count, Mean Platelet Volume and Platelet Distribution Width

Correlation of Type of Species and Parasite Density in Malaria With Platelet Count, Mean Platelet Volume and Platelet Distribution Width

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Clinical spectrum and treatment outcome of severe malaria caused byPlasmodium vivaxin 18 children from northern India

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