Retrospective Drug Utilization Evaluation of Vancomycin Usage in Infectious Wards and Intensive Care Units in Hamedan Teaching Hospitals, April to September 2020

Ghollar, Mohammad Amin; Rangchian, Maryam; Etminaniesfahani, Maryam

doi:10.34172/ajpr.2021.11

Cited by 3 publications

(1 citation statement)

References 6 publications

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“…Nevertheless, it is well known that a certain percentage of patients continue to receive empirical vancomycin treatment inappropriately. (21,22,23 ) Over the last twenty years, a number of studies have evaluated the usage of vancomycin based on its indications. In those investigations, researchers found that, when compared to particular institution criteria and/or CDC recommendations, up to 65% of vancomycin was used inappropriately.…”

Section: Discussionmentioning

confidence: 99%

Appropriate Use of Vancomycin in a Cardiac Surgical Unit

Mekdad,

sayed,

Alkhalaif

2024

Preprint

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Antibiotic resistance is a quickly growing problem, Methicillin-resistant Staphylococcus aureus (MRSA) and VRE are major worries, particularly in developing nations where cost-effectiveness is . Vancomycin usage needs to be controlled to avoid the growth of organisms that are resistant to it. Examining the appropriateness rate of vancomycin use in light of the recommendations of theInfectious Disease Society of America (IDSA) in the cardiac surgery ward was the aim of this study. Methodology: The study was performed retrospectively. Medical records of patients in cardiac wards treated with vancomycin for the past year were identified and selected. Results: Overall, 294 patients were treated with vancomycin. Appropriate use of vancomycin was higher than inappropriate use (p = 0.001). Approximately 41 % (n = 120 ) of patients were given vancomycin for treatment, whereas the rest were given it empirically. Appropriate use of vancomycin was observed in 89.1 % (n =262 ) of patients. However, there was still a high rate of inappropriate vancomycin use (n = 32 , 10.9 %). The most common reason for inappropriate use was continuing to use beyond 72 hours without further evidence of Gram-positive infection. (n = 20 , 62.5 %) of all inappropriate. Conclusions: According to this study, 10.1% of the Vancomycin that was prescribed to our cardiac surgery patients was inappropriate.

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Section: Discussionmentioning

confidence: 99%

Appropriate Use of Vancomycin in a Cardiac Surgical Unit

Mekdad,

sayed,

Alkhalaif

2024

Preprint

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Appropriate use of vancomycin in a cardiac surgical unit

Mekdad,

Alsayed,

Alkhalaif

2024

J Cardiothorac Surg

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A Drug Utilization Evaluation of Intravenous Acetaminophen in Neurology Ward of a Teaching Hospital: A Retrospective Single-Center Cohort Study

Mohseni,

Etminani Esfahani,

Ataei

et al. 2023

Avicenna J Pharm Res

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Background: The administration of intravenous (IV) acetaminophen is increasing worldwide, due to the higher costs of oral and rectal administration; hence, appropriate prescription of IV acetaminophen is highly important. The aim of this study was to check the compliance of injectable acetaminophen prescription based on the patient’s conditions with health protocols in the neurology ward of hospitalized adults in Hamadan, Iran. Methods: A total of 97 patients with the age range of 17-88 years hospitalized in the neurology ward of Shahid Beheshti hospital in Hamadan from April 2021 to September 2021, who received at least 1 dose of IV acetaminophen, were examined in this retrospective single-center cohort study. Demographic information and clinical parameters such as blood urea nitrogen, creatinine, alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, international normalized ratio, the reason for administration, administration dose and intervals, and the number of administration doses with national guidelines underwent an investigation. The data of the study were extracted from the medical records of the patients and analyzed with SPSS software at a confidence level of 95%. Results: The results demonstrated that the indications for injecting acetaminophen were pain (62.9%), fever (32%), and simultaneous pain and fever (5.2%). The average dose of injectable acetaminophen, the duration of administration (minutes), and the administration intervals (hours) were 5.05±0.66, 67.50±6.62, and 12.34±5.37, respectively. The frequency of compliance with the instructions was 21.6% and 72.2% of non-compliance due to the lack of a need for an injectable form while there was the possibility of using an oral or rectal form. Conclusion: Based on the results of this study, the majority of IV acetaminophen in patients admitted to the neurology ward did not comply with national guidelines, and the most common cause of non-compliance was the use of the injectable form of acetaminophen. Moreover, improper administration of IV acetaminophen is not economically beneficial for the healthcare system.

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Retrospective Drug Utilization Evaluation of Vancomycin Usage in Infectious Wards and Intensive Care Units in Hamedan Teaching Hospitals, April to September 2020

Cited by 3 publications

References 6 publications

Appropriate Use of Vancomycin in a Cardiac Surgical Unit

Appropriate Use of Vancomycin in a Cardiac Surgical Unit

Appropriate use of vancomycin in a cardiac surgical unit

A Drug Utilization Evaluation of Intravenous Acetaminophen in Neurology Ward of a Teaching Hospital: A Retrospective Single-Center Cohort Study

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