Retrospective evaluation of corneal reconstruction usingACell Vet^™alone in dogs and cats: 82 cases

Abstract

Corneal reconstruction with ACell Vet(™) alone is a viable alternative and results in minimal scarring and complications in cats. In dogs, scarring is more pronounced than in cats and graft dehiscence rate is higher compared to conventional techniques.

The use of porcine urinary bladder matrix (UBM) to repair a perforated corneal ulcer with iris prolapse in a horse

“…In veterinary medicine it has been reported for use in corneal reconstruction in dogs and cats (Balland et al . ; Chow and Westermeyer ) and for severe ulceration with keratomalacia in horses (Mancuso et al . ).…”

“…Studies in the dog and cat have demonstrated that vascularisation of A cell grafts is usually evident around the second week and that epithelialisation is usually complete by the third week (Chow and Westermeyer ). In contrast, in the equine case reported here, epithelialisation was still incomplete at 3 weeks.…”

“…They also contain growth factors (Balland et al . ; Chow and Westermeyer ). Extracellular bladder matrix products promote cellular proliferation and regeneration and are progressively degraded as local tissues replace the graft.…”

Ulcerative keratitis and keratomalacia in horses: Medical management and surgical considerations

“…Of the studies presented by Mancuso et al . (), Chow and Westermeyer () and Balland et al . (), the overall success rate for the use of UBM alone in ulcerative keratitis was >80%, in terms of the retention of a comfortable and visual eye.…”

“…UBM can also be used as a sole therapy, as has been reported in dogs and cats with varying degrees of ulcerative keratitis, including corneal perforation (Balland et al . ; Chow and Westermeyer ) and in horses with partial thickness ulcerative keratitis (Mancuso et al . ).…”