Retrospective evaluation of pathological results among women with ovarian endometriomas versus teratomas

Abstract

The coexistence of endometrioma with dermoid cyst of the ovaries is an unusual entity, although they are both common and benign gynecological tumors. The present study aimed to investigate the association between ovarian dermoid cyst (teratoma) and endometrioma. We retrospectively, included 315 women with endometrioma and 172 with ovarian teratoma. Data were collected from medical and pathological reports from two different areas between 1995 and 2018. The mean age of cases with endometrioma was similar (35.8±7.2 years) to patients with ovarian teratoma (34.2±6.8 years). Considering the types of dermoid cysts, the observed proportion of mature type was 168/172 (98%), the immature type was 4/172 (2%) and struma ovarii was14/172 (8.1%) respectively. Endometrioma was significantly more frequent in the left ovary [174/266 (65.4%)] than in the right ovary [92/266 (34.6%)], P<0.001. By contrast, ovarian teratoma were predominant in the right ovary, 98/172 (60.6%), compared to the left side, 56/172 (32.5%), P<0.001. Regarding the size of the masses, we detected an inverse distribution between the two groups. Thirteen women were detected with ovarian teratoma and endometriosis, with 6 cases being in the same ovary. Our results indicate a left lateral predispostion of endometrioma and a right of ovarian teratoma and suggest that the pathogenesis between these conditions is different. The coexistence of endometriosis with dermoid cyst of the ovary, presents a challenge to the physicians and the investigators. Further research is required to establish the relationship between endometriosis and ovarian teratoma.

Bilateral ovarian cysts of mature cystic teratoma and Endometrioma: Its surgical challenges and review of literature

“…The serum level of CA 125 is non specific and is often elevated in women with endometriomas and cystic teratomas. In a retrospective study by Matalliotakis et al 7 reported coexistence of teratoma and endometrioma in five cases. Huseyin et al 19 reported two cases of coexistence of teratoma and endometioma.…”

“…Here, the endometrioma was developed in the left ovary and dermoid on right ovary, which is consistent with cases reported in the literature. 6,7…”

Laparoscopic removal of a dermoid cyst in one ovary and an endometrioma in the other: A case report and literature review

“…A total of four articles were found and these are summarized in Table 1 , which shows the coexistence of endometrioma with dermoid cyst including the imaging used for diagnosis and treatment. The first study listed in Table 1 found a total of seven women, whereas the second study reported two women with an endometrioma and a dermoid cyst [ [8] , [9] ]. This makes the present case report the 12th case of a woman diagnosed with co-existing endometrioma and dermoid cyst to our knowledge.…”

Coexistence of mature cystic teratomas and endometriosis

“…They showed that MCTs were found in 1.5% of women with endometriosis. Thereafter, Matalliotakis et al evaluated the association between ovarian dermoid cyst (teratoma) and endometrioma [4]. They showed that the coexistence of ovarian teratoma with endometriosis detected in 4.6% (8/172) of women and with endometrioma in 2.9% (5/172).…”

“…Although MCTs and endometriosis are benign ovarian tumors encountered frequently in women of childbearing age, the coexistence of these two diseases has been reported in only a few case reports so far. However, a few studies describing the coexistence MCTs and endometriosis directly or indirectly have been published recently [3,4,5,6]. Therefore, the author intended to gather and organize available knowledge to help find the clinical implications of this rare and challenging condition and establish a framework for diagnosis and treatment.…”