Retrospective evaluation of the use of amiodarone in dogs with arrhythmias (from 2003 to 2010)

Pedro, Brigite; López-Alvarez, Jordi; Fonfara, Sonja; Stephenson, Hannah; Dukes‐McEwan, J.

doi:10.1111/j.1748-5827.2011.01142.x

Cited by 25 publications

(8 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In another study using client-owned dogs with supraventricular tachyarrhythmia, uncommon gastrointestinal side effects were attributed to oral amiodarone, and the clinical signals improved after the does was reduced to 5 to 7.5 mg/ day. The conclusion was that amiodarone could be a safe and effective alternative for the treatment of arrhythmias that are not controlled with other anti-arrhythmic drugs (PEDRO et al, 2012).…”

Section: Blood Chemistry Resultsmentioning

confidence: 99%

Digoxin for atrial fibrillation: good, but not too good: a case report

Junior

Almeida²,

Santos³

et al. 2022

AVB

View full text Add to dashboard Cite

Digoxin is a cardiotonic glycoside that is traditionally used for the treatment of heart failure and atrial fibrillation in humans and animals. However, the use of digoxin is still a challenge in clinical practice due to its narrow therapeutic range and its potential interaction with several drugs, which could facilitate the development of toxicity. A 12-year-old Labrador retriever was referred with a clinical diagnosis of heart failure and atrial fibrillation, anorexia, vomiting, and diarrhea. He had been medicated with digoxin, furosemide, lisinopril, and amiodarone. The patient also showed clinical signs of hip osteoarthritis and received firocoxib for four days. He additionally received drugs for gastrointeritis. The electrocardiogram demonstrated atrial fibrillation and signs of digitalis toxicity. Laboratory examination showed a high concentration of plasma digoxin, and 5 days after withdrawal of the drugs, the symptoms disappeared, as did the digitalis effects seen in the previous electrocardiogram.

show abstract

Section: Blood Chemistry Resultsmentioning

confidence: 99%

Digoxin for atrial fibrillation: good, but not too good: a case report

Junior

Almeida²,

Santos³

et al. 2022

AVB

View full text Add to dashboard Cite

show abstract

“…Slow, non-sustained VT, also known as accelerated AV rhythm (<120 bpm), with no haemodynamic compromise, may resolve spontaneously and oftentimes does not require treatment 12. Conventional treatment of VT includes lidocaine (up to 8 mg/kg intravenous bolus, followed by a CRI of 50–80 μg/kg/minute CRI), esmolol, procainamide, amiodarone or magnesium 13 14. In this case, immediate identification of the cardiac or extracardiac source of VT would have been ideal for better VT-targeted management, but was not possible.…”

Section: Discussionmentioning

confidence: 99%

Reversal of sustained ventricular tachycardia with magnesium but not with lidocaine in a dog during the perianaesthetic period

Ranninger

Bartoszuk

Kutter

2019

Vet Record Case Reports

View full text Add to dashboard Cite

A one-and-a-half-year-old, male neutered Pyrenean mountain dog was presented with bleeding after orchiectomy at a private veterinary practice. Drops of blood were emerging from the surgical site. Clinical evaluation evidenced slightly pale mucous membranes and a mildly elevated heart rate. Preoperative blood testing revealed a mild hyperlactataemia. Due to the haemorrhage, anaesthesia was induced for surgical ligation of the vessel. During dissection of the testicular vessels, repeated episodes of sudden sustained ventricular tachycardia (heart rate >190 beats per minute, lasting about one minute) and hypotension were observed. Despite repeated intravenous lidocaine boluses (8 mg/kg total) and a constant rate infusion (80 μg/kg/minute), the ventricular tachycardia did not cease. After an intravenous magnesium infusion, a sinus rhythm returned within 20 minutes of administration. In view of ventricular tachycardia resistant to conventional therapies, magnesium administration might be a safe adjuvant pharmacological option, as described in the case herein.

show abstract

“…A second ex vivo controlled study evaluating the effects of amiodarone on thyroid function test results identified inhibition of TSH‐induced secretion of T4 (73% of normal) and T3 (68% of normal) 148 . Finally, a retrospective study of dogs receiving amiodarone for treatment of arrhythmias found no change in serum TT4 and TSH concentrations after a median of 84 and 75 days of treatment, respectively 70 . Health status, study power and design, and amiodarone dose could account for the inconsistent serum TT4 results found between studies.…”

Section: Effects Of Drugs On Thyroid Functionmentioning

confidence: 98%

Influence of medications on thyroid function in dogs: An update

Bolton

Panciera

2023

Veterinary Internal Medicne

View full text Add to dashboard Cite

Erroneous thyroid function test results can occur because of drugs that alter thyroid hormone physiology in one or more aspects, including synthesis, secretion, distribution, and metabolism. Research since publication of the last review in the Journal of Veterinary Internal Medicine (JVIM) 20 years ago has evaluated the effects of amiodarone, zonisamide, inhalant anesthetics, clomipramine, trilostane, and toceranib on thyroid function tests in the dog. In addition, recent work on the effects of glucocorticoids, sulfonamides, phenobarbital, and nonsteroidal anti‐inflammatory drugs will be reviewed. Awareness of these effects is necessary to avoid misdiagnosis of hypothyroidism and unnecessary treatment.

show abstract

Retrospective evaluation of the use of amiodarone in dogs with arrhythmias (from 2003 to 2010)

Abstract: Amiodarone may be an effective and safe alternative to treat supraventricular and ventricular arrhythmias in dogs, when common anti-arrhythmic drugs are not effective or contraindicated.

Cited by 25 publications

References 36 publications

Digoxin for atrial fibrillation: good, but not too good: a case report

Digoxin for atrial fibrillation: good, but not too good: a case report

Reversal of sustained ventricular tachycardia with magnesium but not with lidocaine in a dog during the perianaesthetic period

Influence of medications on thyroid function in dogs: An update

Contact Info

Product

Resources

About