Retrospective multicenter study of surgical treatments for osteoporotic vertebral fractures

Internal fixation with percutaneous kyphoplasty compared with simple percutaneous kyphoplasty for thoracolumbar burst fractures in elderly patients: a prospective randomized controlled trial

“…Vertebral pedicle screws implanted into the spine of elderly patients with thoracolumbar fractures are prone to loosening, which is a relatively common complication. In the present study, however, during the follow-up period of over 2 years, none of the patients in the treatment group exhibited loosening or shifting of their internal fixation device, which differs from previous reports [5][6][7]. The main reason for this difference may be that the anterior and middle spinal columns of our patients were immediately strengthened by the use of bone cement early after the reduction by internal fixation.…”

“…Especially, postoperative complications like the adjacent vertebra fractures or the injured vertebra refractures may often occur, which always lead to severe pain and dysfunction [3,4]. Pedicle screw internal fixation alone can achieve satisfactory reduction but may increase the trauma, and screw loosening often occurs due to senile osteoporosis; there is also a higher incidence of late kyphosis deformity [5][6][7].…”

Does bisphosphonate-based anti-osteoporosis medication affect osteoporotic spinal fracture healing?

“…However, six patients (5.7 %; three in each group) showed impaired facture healing with evidence of an IVC and fracture instability. The prevalence is similar to that of one multicenter study reporting the prevalence of OSFs with neurological compromises [21]. Since impaired healing of OSFs has not been defined, we arbitrarily defined the presence of an IVC, progression of kyphosis, and collapse of the involved vertebra at rates exceeding the mean as evidence of impaired healing.…”

Percutaneous Vertebroplasty of the Entire Thoracic and Lumbar Vertebrae for Vertebral Compression Fractures Related to Chronic Glucocorticosteriod Use: Case Report and Review of Literature

“…These fractures not only reduce the patient's quality of life, but can also lead to multiple comorbidities such as functional limitations, depression, disability, height loss, spinal instability, and kyphotic deformity associated with impaired lung capacity. Unfortunately, conservative treatment strategies, such as analgesia, bed rest, and physical therapy, and other surgical options do not appear to effectively manage the disease ( 1 , 2 ). Although the surgical treatment of spine deformities can be very challenging due to the frequently poor bone quality and to the patient's expectations regarding the improvement of chronic pain, which need to be clarified upfront, percutaneous vertebroplasty has become an interesting treatment option to improve functionality and quality of life and for the management of acute pain resulting from vertebral fractures, based on recent clinical results, especially for elderly patients ( 3 , 4 , 5 ).…”