Retrospective Multicenter Survey on Food-Related Symptoms Suggestive of Cow’s Milk Allergy in NICU Neonates

Miyazawa, Tokuo; Itabashi, Kazuo; Imai, Takanori

doi:10.2332/allergolint.11-oa-0417

Cited by 36 publications

(35 citation statements)

References 17 publications

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“…The clinical features repeat every single time the child eats the culprit food, and it is totally resolved once these proteins are removed from the diet . Although several reports have been published in the past few years, there is still a lack of knowledge about this syndrome, its epidemiology, and its clinical characteristics FPIES is thought to be a cell‐mediated disorder but is uncertain about the role of specific IgE in this pathology. It has been speculated that there might be a local IgE production in the intestinal mucosa that participates in reaction to the food but would not reach the blood stream …”

Section: Introductionmentioning

confidence: 99%

Food protein‐induced enterocolitis syndrome by fish: Not necessarily a restricted diet

Infante

Martín

Sanchez-Dominguez

et al. 2017

Allergy

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Food protein-induced enterocolitis syndrome (FPIES) is a non-IgE-mediated gastrointestinal food hypersensitivity usually due to cow's milk or soy. Recent researches show that fish is 1 of the most important triggers of FPIES in the Mediterranean countries. Due to the risk of multiple-food FPIES, avoiding foods in the same category or that often occur together may be reasonable. The aim of this study was to evaluate the evolution and follow-up of FPIES related to fish over a period of 20 years. We describe the clinical features of our population, discuss different approaches to oral food challenges, and analyze the possibility of introducing the culprit fish or other nonrelated fish to avoid unnecessary restricted diets.

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Section: Introductionmentioning

confidence: 99%

Food protein‐induced enterocolitis syndrome by fish: Not necessarily a restricted diet

Infante

Martín

Sanchez-Dominguez

et al. 2017

Allergy

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“…According to our review of the literature, apneic attacks appear as a rare symptom of neonatal gastrointestinal allergy at a frequency of 4.5% 1,2) . This neonatal gastrointestinal allergy especially to cow's milk is one of the non -IgEmediated food allergies.…”

Section: Discussionmentioning

confidence: 99%

“…His serum level of immunoglobulin (Ig)E was <5 IU/mL, and he was negative for cow's milkspecific IgE. Additional diagnostic tests such as allergenspecific lymphocyte stimulation test and fecal eosinophils were not performed at this time because the falsepositive rate is high in this condition 1,2) . Changes in the profiles of 17 different cytokines including IFNγ are shown in the table 2) .…”

Section: Case Reportmentioning

confidence: 99%

“…Gastrointestinal food allergy in neonates in Japan has increased dramatically since the end of the 1990s and has become a relative common disease in recent years 1,2) . In the neonatal period, food allergy revealed mainly through gastrointestinal symptoms such as bloody stool, vomiting and abdominal distension has recently been attracting attention as being indicative of gastrointestinal food allergy in neonates 3) .…”

Section: Introductionmentioning

confidence: 99%

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A male preterm infant with cow’s milk allergy to human milk fortifier showing only severe respiratory symptoms

Nakamura

Hatanaka

Kashima

et al. 2019

FJMS

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We report a male infant with a birthweight of 1,400 g at 29 weeks 2 days gestation diagnosed as having cow's milk allergy (CMA) due to human milk fortifier, who developed severe respiratory symptoms. The infant had no gastrointestinal symptoms ; rather, the initial symptoms were apnea attacks and wheezing with a prolonged expiratory phase that progressed to severe ventilatory insufficiency requiring mechanical ventilation. Aggravation of his general condition, which appeared to be due to sepsis, was improved by temporary starvation and respiratory care, but he relapsed on the resumption of enteral feeding of his mother's milk with a human milk fortifier. As a result, this event was interpreted as a positive oral food challenge test. The infant resumed complete breastfeeding without the fortifier and has not relapsed since. Examination of his serial cytokine profiles from residual serum revealed that although interleukin-5 was not increased, interferon (IFN)-γ was increased, suggesting some relation between the time course of IFNγ and the infant's eosinophil count. These findings may indicate that the involvement of IFNγ is one cause of the onset of this disease.

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“…Milk-specific IgE is usually not established in newborns with CMA. Therefore, an oral food challenge test should be the main diagnostic method for CMA (3). If the infant has been fed with formula milk, the formula should be changed to an extensively hydrolyzed formula or amino acid formula (4).…”

Section: Urticaria Due To Cow's Milk Allergy In An Exclusively Breastmentioning

confidence: 99%

Urticaria Due to Cow’s Milk Allergy in a Newborn

İlhan¹,

Ozer²,

Ozdemir³

et al. 2016

West Indian Med J

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Retrospective Multicenter Survey on Food-Related Symptoms Suggestive of Cow’s Milk Allergy in NICU Neonates

Cited by 36 publications

References 17 publications

Food protein‐induced enterocolitis syndrome by fish: Not necessarily a restricted diet

Food protein‐induced enterocolitis syndrome by fish: Not necessarily a restricted diet

A male preterm infant with cow’s milk allergy to human milk fortifier showing only severe respiratory symptoms

Urticaria Due to Cow’s Milk Allergy in a Newborn

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