Retrospective study 2005–2015 of all cases of fetal death occurred at ≥23 gestational weeks, in Friuli Venezia Giulia, Italy

Monasta, Lorenzo; Giangreco, Manuela; Ancona, E.; Barbone, Fabio; Bet, Elisa; Boschian-Bailo, Pierino; Cacciaguerra, Giovanna; Cagnacci, Angelo; Canton, Melania; Casarotto, Maddalena; Comar, Manola; Contardo, S.; Agostini, Michela; Seta, Francesco De; Ben, Giovanni Del; Loreto, Carla Di; Driul, Lorenza; Facchin, Stefano; Giornelli, Roberta; Ianni, A.; Valle, Santo La; Londero, Ambrogio P.; Manfe, M.; Maso, Gianpaolo; Mugittu, Raffaela; Olivuzzi, Monica; ­Orsaria, Maria; Pecile, Vanna; Pinzano, R.; Pirrone, Francesco; Quadrifoglio, Mariachiara; Ricci, Giuseppe; Ronfani, Luca; Salviato, Tiziana; Sandrigo, Elisa; Smiroldo, Silvia; Sorz, Alice; Stampalija, Tamara; Urriza, Marianela; Vanin, M; Verardi, Giuseppa; Alberico, Salvatore

doi:10.1186/s12884-020-03074-9

Cited by 8 publications

(5 citation statements)

References 23 publications

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“…It has been reported that the causes of perinatal mortality change due to the progress in prenatal diagnosis and perinatal management [ 5 - 6 ]. Fresh stillbirth reflects the quality of intrapartum care, while macerated stillbirth reflects antenatal care (ANC) quality [ 7 - 8 ].…”

Section: Introductionmentioning

confidence: 99%

Incidence and Causes of Stillbirth in Omdurman Maternity Hospital, Sudan: A Prospective Cross-Sectional Study

Alsammani¹

2021

Cureus

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Background: Stillbirth is an important indicator of the quality of antenatal health services. This study aimed to identify the incidence and causes of stillbirths among Sudanese women. Method: This is a descriptive cross-sectional hospital-based study that was conducted at Omdurman Maternity Hospital during the period from December 1, 2019 to May 30, 2020. The study sample comprised 285 women who presented with stillbirths. Data were collected using a structured questionnaire administered to women after taking informed consent. Data were analyzed using descriptive statistics [Statistical Package for Social Sciences (SPSS) version 24 (IBM Corp., Armonk, NY)]. Results: The incidence of stillbirths was 16/1000. Idiopathic causes were the most frequent causes which accounted for 20% (n=57), followed by pre-eclampsia 18.6% (n=53), congenital abnormalities 15.1% (n=43), and abruption placentae 14.4% (n=41). In addition, the less common causes were eclampsia 4.6% (n=13), ruptured uterus 4.2% (n=12), twin-twin transfusion 4.2% (n=12), cord prolapse 3.5% (n=10), uncontrolled diabetes mellitus (DM) 3.5% (n=10), malpresentation 2.6% (n=8), gestational DM 2.5%(n=7), anemia 2.5%(n=7), sepsis 2.1 (n=6), placenta previa 1.4% (n=4), renal disease 0.4% (n=1), and toxoplasmosis 0.4% (n=1). Conclusion: The incidence of stillbirths was 16/1000. Unexplained causes of stillbirths were the most common causes which accounted for 20% of all deaths. In contrast, explainable causes were responsible for 80% of fetal deaths. Among explainable causes, pre-eclampsia and its consequences (abruption, eclampsia) remain the most common cause.

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Section: Introductionmentioning

confidence: 99%

Incidence and Causes of Stillbirth in Omdurman Maternity Hospital, Sudan: A Prospective Cross-Sectional Study

Alsammani¹

2021

Cureus

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“…In 2013, the fetal death rate of 5.96 per 1,000 live births and fetal deaths, described in the USA (McDorman & Gregory, 2015), was lower than the Latin American stillbirth rate (9.6 per 1,000). Also lower than ReLAMC, the rate of fetal deaths at ≥23 weeks was 2.8 per 1,000 live births, in Friuli Venezia Giulia, 2005 to 2013, excluding TOPFA (Monasta et al, 2020). Lower stillbirth rates were also published for Australia, 7.1 per 1,000, from 2013 to 2014 (Australian Institute of Health and Welfare, 2018), and the U.K. stillbirth rate is 3.74 per 1,000 (Draper et al, 2019).…”

Section: Discussionmentioning

confidence: 92%

The Latin American network for congenital malformation surveillance: ReLAMC

Orioli

Dolk

López-Camelo

et al. 2020

American J of Med Genetics Pt C

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The early detection of congenital anomaly epidemics occurs when comparing current with previous frequencies in the same population. The success of epidemiologic surveillance depends on numerous factors, including the accuracy of the rates available in the base period, wide population coverage, and short periodicity of analysis. This study aims to describe the Latin American network of congenital malformation surveillance: ReLAMC, created to increase epidemiologic surveillance in Latin America. We describe the main steps, tasks, strategies used, and preliminary results. From 2017 to 2019, five national registries (Argentina [RENAC], Brazil [SINASC/SIM‐BRS], Chile [RENACH], Costa Rica [CREC], Paraguay [RENADECOPY‐PNPDC]), six regional registries (Bogotá [PVSDC‐Bogota], Cali [PVSDC‐Cali], Maule [RRMC SSM], Nicaragua [SVDC], Nuevo‐León [ReDeCon HU], São Paulo [SINASC/SIM‐MSP]) and the ECLAMC hospital network sent data to ReLAMC on a total population of 9,152,674 births, with a total of 101,749 malformed newborns (1.1%; 95% CI 1.10–1.12). Of the 9,000,651 births in countries covering both live and stillbirths, 88,881 were stillborn (0.99%; 95% CI 0.98–0.99), and among stillborns, 6,755 were malformed (7.61%; 95% CI 7.44–7.79). The microcephaly rate was 2.45 per 10,000 births (95% CI 2.35–2.55), hydrocephaly 3.03 (2.92–3.14), spina bifida 2.89 (2.78–3.00), congenital heart defects 15.53 (15.27–15.79), cleft lip 2.02 (1.93–2.11), cleft palate and lip 2.77 (2.66–2.88), talipes 2.56 (2.46–2.67), conjoined twins 0.16 (0.14–0.19), and Down syndrome 5.33 (5.18–5.48). Each congenital anomaly showed heterogeneity in prevalence rates among registries. The harmonization of data in relation to operational differences between registries is the next step in developing the common ReLAMC database.

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“…Intrauterine fetal demise (IUFD) occurs when a fetus dies in utero after 20 weeks of gestation [ 4 ]. The prevalence of IUFD varies greatly between areas and nations, ranging from 2.5 to 8.8 per 1,000 newborns [ 5 ]. The causes of IUFD are multifactorial and include maternal, fetal, and placental factors.…”

Section: Introductionmentioning

confidence: 99%

A Rare Case of Portal Hypertension and Ascites Following Intrauterine Fetal Death: A Case Report

Shah,

Priyatha,

Ali

et al. 2024

Cureus

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We present a rare case of a 25-year-old woman who developed idiopathic portal hypertension and ascites four days after delivering a stillborn child at term. She had no previous liver illness or risk factors for portal vein thrombosis. Investigations revealed a dilated portal vein, esophageal varices, and high serum-albumin gradient ascites, all of which point to a presinusoidal etiology of portal hypertension. There was no indication of cirrhosis, hepatic or portal vein thrombosis, metabolic or autoimmune liver diseases, or persistent infections. She was treated with antibiotics, diuretics, and beta-blockers, and she underwent a therapeutic paracentesis. The etiology of her portal hypertension remains undetermined. Idiopathic portal hypertension is a rare condition of unknown etiology, characterized by portal hypertension without cirrhosis or thrombosis. It is linked to several risk factors and histological abnormalities, and it can be accompanied by portal hypertension consequences, such as variceal hemorrhage and ascites. The diagnosis is made using clinical criteria and the elimination of alternative causes of portal hypertension. Management is mostly symptomatic, intending to avoid and treat portal hypertension consequences. The prognosis varies according to the underlying etiology and presence of complications.

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Retrospective study 2005–2015 of all cases of fetal death occurred at ≥23 gestational weeks, in Friuli Venezia Giulia, Italy

Cited by 8 publications

References 23 publications

Incidence and Causes of Stillbirth in Omdurman Maternity Hospital, Sudan: A Prospective Cross-Sectional Study

Incidence and Causes of Stillbirth in Omdurman Maternity Hospital, Sudan: A Prospective Cross-Sectional Study

The Latin American network for congenital malformation surveillance: ReLAMC

A Rare Case of Portal Hypertension and Ascites Following Intrauterine Fetal Death: A Case Report

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