Retrospective Study of the Safety and Efficacy of Intraoperative Methadone for Pain Management in Patients Undergoing Elective Intracranial Surgery

Vandse, Rashmi; Vacaru, Alexandra; Propp, Dennis; Graf, Justin; Sran, Jasmine; Pillai, Padmanabhan

doi:10.1016/j.wneu.2023.04.053

World Neurosurgery

2023

DOI: 10.1016/j.wneu.2023.04.053

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Retrospective Study of the Safety and Efficacy of Intraoperative Methadone for Pain Management in Patients Undergoing Elective Intracranial Surgery

Rashmi Vandse¹,

Alexandra Vacaru²,

Dennis Propp³

et al.

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2024

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Cited by 2 publications

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An update on the perioperative management of postcraniotomy pain

Dean,

McCullough,

Papangelou

2024

Current Opinion in Anaesthesiology

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Purpose of review Pain after craniotomy is often severe and undertreated. Providing adequate analgesia while avoiding medication adverse effects and physiological complications of pain remains a perioperative challenge. Recent findings Multimodal pain management includes regional anesthesia and analgesic adjuncts. Strategies aim to reduce or eliminate opioids and the associated side effects. Many individual pharmacologic interventions have been studied with beneficial effects on acute pain following craniotomy. Evidence has been accumulating in support of scalp blockade, nonsteroidal anti-inflammatory drugs (NSAIDs), dexmedetomidine, paracetamol, and gabapentinoids. The strongest evidence supports scalp block in reducing postcraniotomy pain and opioid requirements. Summary Improving analgesia following craniotomy continues to be a challenge that should be managed with multimodal medications and regional techniques. Additional studies are needed to identify the most effective regimen, balancing efficacy and adverse drug effects.

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An update on the perioperative management of postcraniotomy pain

Dean,

McCullough,

Papangelou

2024

Current Opinion in Anaesthesiology

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Progress in the Study of Postoperative Complications of Vestibular Schwannomas

李

2024

ACM

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Retrospective Study of the Safety and Efficacy of Intraoperative Methadone for Pain Management in Patients Undergoing Elective Intracranial Surgery

Cited by 2 publications

References 28 publications

An update on the perioperative management of postcraniotomy pain

An update on the perioperative management of postcraniotomy pain

Progress in the Study of Postoperative Complications of Vestibular Schwannomas

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