Reusing the patent internal mammary artery as a conduit in redo coronary artery bypass surgery: Table 1:

Abstract

A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was, in patients with previous internal mammary artery/internal thoracic artery (ITA) grafts, can the internal mammary artery/ITA be reused/recycled in redo coronary artery bypass surgery? Fourteen papers were found using the reported search of which 10 represented the best evidence to answer the clinical question. There was variation in patient selection, the number of patients reported, outcome measures recorded, and methods and duration of follow-up. The results were mostly in favour of using a recycled ITA when it could be safely harvested. Most studies were retrospective. One large series of 60 patients who underwent redo coronary artery bypass grafting (CABG) using previously implanted ITAs had a mean time to reoperation of 117 ± 68 months. They reported no operative deaths; no patients required further or subsequent target vessel revascularization; 30-day mortality was 8.3% and myocardial infarction rate was 3%. Another two series of 16 and 12 patients underwent recycling of arterial grafts during coronary artery revascularization with no perioperative deaths in either. Postoperative angiography was performed in 10 patients in one of these studies, which showed excellent flow in all redone left internal thoracic artery (LITA) grafts. One study reported results from a prospective cohort of 9 patients who underwent redo coronary artery bypass grafting. Interval between operations was between 1 and 132 months. There was no perioperative mortality, but 1 patient required reintervention (to an interposition vein graft). A further study of 4 patients who underwent redo CABG using ITAs that were patent but with severe stenosis at the distal anastomosis had no mortality. Postoperative angiography showed patency of all grafts. There have also been 4 case reports on reusing the ITA/ITA in redo CABG with no damage to the reused LITA, no perioperative mortality and satisfactory follow-up at up to 29 months. Evidently, the recycled ITA can be used in redo coronary artery bypass grafting. Papers found were retrospective series or case reports. As such, there is no direct comparison in outcomes between the recycled ITA and first-time ITA harvest or any other conduit for CABG. In conclusion, we find that when it is possible to harvest a previously used ITA, studies have shown it to be a safe and viable conduit in redo CABG with good long-term outcomes.

Cardioprotective role of arterial conduits

“…Наиболее вероятным объяснением может быть именно наличие питающей ножки самого артериального трансплантата, которая максимально приближает создаваемую систему кондуита и нативной КА к физиологической, когда поток крови не только является естественным в проксимальном участке, но и не повреждается единство эндотелиального слоя. Тот факт, что ВГА можно с успехом использовать даже при повторных КШ, сохраняя свое положение «in situ», говорит о высоком анатомо-физиологическом потенциале, так как, вероятно, наличие проксимально отходящей ВГА от подключичной артерии в неотсеченном виде для использования ее как свободного графта имеет особое значение в долгосрочном функционировании кондуита [6]. Кроме этого, доказано, что ВГА с физиологической точки зрения является важным донором оксида азота (NO)/простациклина, имеет высокий резервный кровоток, высокую способность к вазодилатации, низкую чувствительность к вазоспазму, в ответ на тромбин отвечает релаксацией, а процесс липолиза в стенке происходит достаточно быстро, устраняя тем самым плацдарм для развития атеросклероза [7].…”