2013
DOI: 10.1111/iej.12107
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Revascularization of an immature tooth with a necrotic pulp using platelet‐rich fibrin: a case report

Abstract: Platelet-rich fibrin might serve as a potentially ideal scaffold in revascularization of immature permanent teeth with necrotic pulps as it is rich in growth factors, enhances cellular proliferation and differentiation, and acts as a matrix for tissue ingrowth.

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Cited by 106 publications
(74 citation statements)
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“…PRF as a scaffolding material in an infected necrotic immature tooth for pulpal regeneration and tooth revitalization as it satisfies many criteria of an ideal physical scaffold [1]. Triple antibiotic paste was used for disinfection of the canal because this particular combination is effective in addressing the diverse flora present in the root canal.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…PRF as a scaffolding material in an infected necrotic immature tooth for pulpal regeneration and tooth revitalization as it satisfies many criteria of an ideal physical scaffold [1]. Triple antibiotic paste was used for disinfection of the canal because this particular combination is effective in addressing the diverse flora present in the root canal.…”
Section: Discussionmentioning
confidence: 99%
“…Platelet-rich fibrin might serve as a potentially ideal scaffold in revascularization of immature permanent teeth with necrotic pulps as it is rich in growth factors, enhances cellular proliferation and differentiation, and acts as a matrix for tissue ingrowth [1].…”
mentioning
confidence: 99%
“…[33] Platelet rich fibrin:-PRF is known as a second-generation platelet concentrate. [35] PRF was developed first by Choukroun et al (2001) [36] this simplified and cost-effective chair side procedure results in a resorbable fibrin matrix enriched with platelets and leukocytes. PRF provides a rich source of growth factors, including platelet derived growth factors (PDGFs), transforming growth factors (TGFs), vascular endothelial growth factor (VEGF), and insulin-like growth factor (IGF) [36] The growth factors are slowly released during the course of the healing process.…”
Section: Issn: 2320-5407mentioning
confidence: 99%
“…La necesidad de colecta de sangre en pacientes jóvenes, equipo especial y alto costo del tratamiento podrían ser considerados como desventajas de esta terapia. Sin embargo, en base a estudios clínicos y radiográ-fi cos, estos materiales son una importante opción en casos en los que la inducción del sangramiento no tuvo éxito (47,50,51).…”
Section: Revascularización Pulparunclassified