2024 Help me understand this report
Revealing curcumin therapeutic targets on SRC, PPARG, MAPK8 and HSP90 as liver cirrhosis therapy based on comprehensive bioinformatic study
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“…It was also found that high expression of HSP90AB1 and HSP90AAl was associated with poor prognosis of PCa [ 44 ]. Curcumin binds to HSP90AA1 and inhibits the growth of hepatocellular carcinoma/glioblastoma and neuroblastoma cells [ 62 ]. This finding indirectly suggests that curcumin may inhibit the growth of prostate cancer cells by binding to HSP90AA1/HSP90AB1; however, further experimental validation is needed to confirm this conclusion.…”
Section: Discussionmentioning
confidence: 99%
“…It was also found that high expression of HSP90AB1 and HSP90AAl was associated with poor prognosis of PCa [ 44 ]. Curcumin binds to HSP90AA1 and inhibits the growth of hepatocellular carcinoma/glioblastoma and neuroblastoma cells [ 62 ]. This finding indirectly suggests that curcumin may inhibit the growth of prostate cancer cells by binding to HSP90AA1/HSP90AB1; however, further experimental validation is needed to confirm this conclusion.…”
Section: Discussionmentioning
confidence: 99%
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