2007
DOI: 10.1097/cad.0b013e328223f14d
|View full text |Cite
|
Sign up to set email alerts
|

Reversal effect of BM-cyclin 1 on multidrug resistance in C-A120 cells

Abstract: In this study, multidrug-resistant human epidermoid C-A120 cells and the sensitive parental KB cells were used as experimental models. BM-cyclin 1, a traditional antimycoplasma drug, was tested to explore the reversal effect of multidrug resistance and its mechanisms in these cell lines. The MTT analysis showed that BM-cyclin 1 could reverse multidrug resistance effectively in C-A120 cells; the sensitivity of C-A120 cells to adriamycin, etoposide and cisplatin was enhanced by 6.0, 8.2 and 1.7 times, respective… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2

Citation Types

0
2
0

Year Published

2012
2012
2013
2013

Publication Types

Select...
2

Relationship

0
2

Authors

Journals

citations
Cited by 2 publications
(2 citation statements)
references
References 19 publications
0
2
0
Order By: Relevance
“…The cytotoxicities of DDP, CBDCA and L-OHP were determined by MTT assay according to the method described [14]. The dose-response curve could be plotted with 50% inhibitory concentration (IC 50 ).…”
Section: Methodsmentioning
confidence: 99%
See 1 more Smart Citation
“…The cytotoxicities of DDP, CBDCA and L-OHP were determined by MTT assay according to the method described [14]. The dose-response curve could be plotted with 50% inhibitory concentration (IC 50 ).…”
Section: Methodsmentioning
confidence: 99%
“…The protein expressions of ATP7A and GAPDH were determined using immunoblotting according to the method described [14]. Primary antibodies were diluted in a blocking solution 1: 500 for ATP7A (Abcam, Cambrige, UK) and 1:5000 for GAPDH (Boster, Wuhan, China).…”
Section: Methodsmentioning
confidence: 99%