Reversal of Poliosis and Vitiligo Following Vogt-Koyanagi-Harada Disease

Abstract

Author Contributions: Dr Kumagai had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis. Financial Disclosure: None reported.

Unusual case of vitiligo reversal in Vogt–Koyanagi–Harada syndrome

“…[ 5 ] Vitiligo reversal in VKH syndrome following systemic immunosuppression has been mentioned in only one previous study. [ 6 ] This paper supports the observation by author of the article aforementioned.…”

Successful Treatment of Vitiligo Associated with Vogt–Koyanagi–Harada Disease

“…Most publications are ophthalmology based and treatment is discussed in the context of managing the syndrome as a whole . The integumentary changes may be permanent, but there is a published case series suggesting that vitiligo and poliosis may be reversible with systemic immunotherapy . Our patient's ocular and neurologic symptoms were in remission and systemic therapy was not indicated for his vitiligo.…”

Poliosis, hair pigment dilution, and premature graying of the hair: A diagnostic approach in pediatric patients and review of the literature

“…It is also important to note that following treatment with prednisone, vitiligo, and poliosis was found to reverse in VKH patients. 33 Less commonly, poliosis in childhood has been seen as a presenting sign in several cases of Alezzandrini syndrome-a segmental form of melanocyte destruction. 34 Other manifestations of Alezzandrini often present in adulthood and include hearing abnormalities and unilateral retinal degeneration with ipsilateral facial vitiligo.…”