Reversal of pulmonary hypertension in a sugen/hypoxic rat model using an ASK1 inhibitor

Wilson, Kevin S.; Buist, Hanna; Jayasekera, Geeshath; Liles, John T.; Budas, Grant R.; Fairfax, Seth T.; Hughes, Colin; Nilsen, Margaret; Church, Colin; MacLean, Margaret R.; Peacock, Andrew J.; Welsh, David

doi:10.1183/1393003.congress-2017.oa4663

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“…A promising study presented by Kathryn Wilson demonstrated that an apoptosis signal-regulating kinase 1 (ASK1) inhibitor was able to reverse RVSP and vascular remodelling in a rat model of sugen-hypoxia induced PH [ 33 ]. This study provided a direct translational link to a session highlighting new clinical trials results in PH therapy.…”

Section: Assembly 13mentioning

confidence: 99%

Early Career Members at the ERS International Congress 2017: highlights from the Assemblies

Kahn¹,

Tomos²,

Andrianopoulos³

et al. 2017

Breathe

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The 2017 ERS International Congress was, as always, well organised, providing participants with a good mixture of translational and clinical science. Early career members were very well represented in thematic poster, poster discussion and oral presentation sessions and were also actively involved in chairing sessions. The efforts of the Early Career Members Committee (ECMC) to increase the number of early career members included in the competence list (the list of early career members with an interest in being more actively involved in the society) paid off immensely, because the number of early career members registered improved hugely across all assemblies after the Congress. Several newly registered early career members have collated some highlights of the Congress for their assemblies, which should be of interest to all members. As assemblies 12 and 13 are new, there is no report from assembly 12 as there is not yet, at the time of writing, an early career member representative for this newly created assembly.

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Section: Assembly 13mentioning

confidence: 99%