Limited information is available in the literature regarding the energy consumption and the greenhouse gases emitted during landfill leachates treatment. A full-scale landfill leachates treatment system that included primary sedimentation, biological treatment in sequencing batch reactors, reverse osmosis and mechanical vapor recompression evaporation was monitored and evaluated for the removal of major pollutants, energy consumption and greenhouse gas emissions. Samples were taken during a period of two years from different points of the system, while the actual power consumption was calculated considering the available mechanical equipment and the hours of operation. The quantities of greenhouse gases emitted were estimated using appropriate equations and based on the operational characteristics of the system. According to chemical analyses, biological treatment resulted in partial removal of COD and total nitrogen, while the removal of BOD5 and NH4-N was significant, reaching 90 and 98%, respectively. Use of reverse osmosis increased the removal of all pollutants, satisfying the requirements of the legislation on wastewater discharge into the environment. Power consumption was calculated to be 35.3 KWhr per m3 of treated leachate, while mechanical vapor recompression evaporation was responsible for 60.5% of the total energy required. The contribution of other processes to energy consumption was as follows, in decreasing order: sequencing batch reactors > reverse osmosis > primary treatment. The roots blower vacuum pump used for mechanical vapor recompression evaporation, and the blowers providing air to the sequencing batch reactors, were the most energy-intensive pieces of apparatus, contributing 44.2% and 11.3% of the required energy, respectively. The quantity of greenhouse gases emitted was estimated to be 27.7 Kg CO2eq per m3 of treated leachates. Among the different processes used, biological treatment and mechanical vapor recompression evaporation contributed to 45.7% and 44.1% of the total emissions, respectively. The findings of this study reveal that an integrated landfill leachate treatment system that combines biological treatment and reverse osmosis can assure the protection of the aquatic environment by producing high-quality effluent; however, further research should be conducted regarding the sustainable management of reverse osmosis concentrate. Mechanical vapor recompression evaporation contributes significantly to the environmental footprint of the landfill leachates treatment system due to both high energy consumption and elevated emissions of greenhouse gases.